KV2A5_MOUSE
ID KV2A5_MOUSE Reviewed; 113 AA.
AC P03976;
DT 23-OCT-1986, integrated into UniProtKB/Swiss-Prot.
DT 23-OCT-1986, sequence version 1.
DT 25-MAY-2022, entry version 91.
DE RecName: Full=Ig kappa chain V-II region 17S29.1;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP PROTEIN SEQUENCE.
RC TISSUE=Hybridoma;
RX PubMed=6441768; DOI=10.1515/bchm2.1984.365.2.1375;
RA Aebersold R., Herbst H., Grutter T., Chang J.Y., Braun D.G.;
RT "Murine V kappa 25 and V kappa 27 amino-acid sequences of C57B1/6 origin:
RT monoclonal antibodies 17S29.1 and 22S25.1 specific for the group A-
RT streptococcal polysaccharide.";
RL Hoppe-Seyler's Z. Physiol. Chem. 365:1375-1383(1984).
CC -!- FUNCTION: Anti-streptococcal group A carbohydrate antibody.
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DR PIR; A01912; KVMS17.
DR PDB; 3CFB; X-ray; 1.60 A; A/L=1-113.
DR PDB; 3CFC; X-ray; 1.70 A; L=1-113.
DR PDBsum; 3CFB; -.
DR PDBsum; 3CFC; -.
DR AlphaFoldDB; P03976; -.
DR SMR; P03976; -.
DR CPTAC; non-CPTAC-3837; -.
DR MaxQB; P03976; -.
DR PRIDE; P03976; -.
DR EvolutionaryTrace; P03976; -.
DR Proteomes; UP000000589; Unplaced.
DR RNAct; P03976; protein.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR GO; GO:0006955; P:immune response; IBA:GO_Central.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; SSF48726; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Adaptive immunity; Direct protein sequencing; Disulfide bond;
KW Hybridoma; Immunity; Immunoglobulin; Reference proteome.
FT CHAIN 1..>113
FT /note="Ig kappa chain V-II region 17S29.1"
FT /id="PRO_0000059774"
FT REGION 1..23
FT /note="Framework-1"
FT REGION 24..39
FT /note="Complementarity-determining-1"
FT REGION 40..54
FT /note="Framework-2"
FT REGION 55..61
FT /note="Complementarity-determining-2"
FT REGION 62..93
FT /note="Framework-3"
FT REGION 94..102
FT /note="Complementarity-determining-3"
FT REGION 103..112
FT /note="Framework-4"
FT DISULFID 23..93
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT NON_TER 113
SQ SEQUENCE 113 AA; 12390 MW; 4E93797046F8DB33 CRC64;
DIVMTQAVFS NPVTLGTSAS ISCRSSKSLL HSNGITYLYW YLQKPGQSPQ LLLYQMSNLA
SGVPDRFSSS GSGTDFTLRI SRVEAEDVGV YYCAHNLELP YTFGGGTKLE IKR
