ID   KV3AD_MOUSE             Reviewed;         111 AA.
AC   P01665;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=Ig kappa chain V-III region PC 7043;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=103003; DOI=10.1038/276785a0;
RA   Weigert M., Gatmaitan L., Loh E., Schilling J., Hood L.E.;
RT   "Rearrangement of genetic information may produce immunoglobulin
RT   diversity.";
RL   Nature 276:785-790(1978).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 10-99.
RX   PubMed=7691608; DOI=10.1002/eji.1830231019;
RA   Mo J.A., Bona C.A., Holmdahl R.;
RT   "Variable region gene selection of immunoglobulin G-expressing B cells with
RT   specificity for a defined epitope on type II collagen.";
RL   Eur. J. Immunol. 23:2503-2510(1993).
RN   [3]
RP   STRUCTURE BY NMR OF 1-111.
RX   PubMed=10801487; DOI=10.1016/s0969-2126(00)00119-2;
RA   Tugarinov V., Zvi A., Levy R., Hayek Y., Matsushita S., Anglister J.;
RT   "NMR structure of an anti-gp120 antibody complex with a V3 peptide reveals
RT   a surface important for co-receptor binding.";
RL   Structure 8:385-395(2000).
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DR   EMBL; Z25444; CAA80931.1; -; mRNA.
DR   EMBL; Z25446; CAA80933.1; -; mRNA.
DR   EMBL; Z25448; CAA80935.1; -; mRNA.
DR   EMBL; Z25450; CAA80937.1; -; mRNA.
DR   EMBL; Z25452; CAA80939.1; -; mRNA.
DR   EMBL; Z25454; CAA80941.1; -; mRNA.
DR   EMBL; Z25458; CAA80945.1; -; mRNA.
DR   PIR; A01937; KVMS43.
DR   PDB; 1F11; X-ray; 3.00 A; A/C=1-111.
DR   PDB; 1QNZ; NMR; -; L=1-111.
DR   PDB; 2ZCH; X-ray; 2.83 A; L=1-111.
DR   PDB; 2ZCK; X-ray; 3.10 A; L=1-111.
DR   PDB; 2ZCL; X-ray; 3.25 A; L=1-111.
DR   PDBsum; 1F11; -.
DR   PDBsum; 1QNZ; -.
DR   PDBsum; 2ZCH; -.
DR   PDBsum; 2ZCK; -.
DR   PDBsum; 2ZCL; -.
DR   AlphaFoldDB; P01665; -.
DR   BMRB; P01665; -.
DR   SMR; P01665; -.
DR   MINT; P01665; -.
DR   MaxQB; P01665; -.
DR   PRIDE; P01665; -.
DR   EvolutionaryTrace; P01665; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; P01665; protein.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR   GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; IBA:GO_Central.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Adaptive immunity; Direct protein sequencing; Disulfide bond;
KW   Immunity; Immunoglobulin; Reference proteome.
FT   CHAIN           1..>111
FT                   /note="Ig kappa chain V-III region PC 7043"
FT                   /id="PRO_0000059787"
FT   REGION          1..23
FT                   /note="Framework-1"
FT   REGION          24..38
FT                   /note="Complementarity-determining-1"
FT   REGION          39..53
FT                   /note="Framework-2"
FT   REGION          54..60
FT                   /note="Complementarity-determining-2"
FT   REGION          61..92
FT                   /note="Framework-3"
FT   REGION          93..101
FT                   /note="Complementarity-determining-3"
FT   REGION          102..111
FT                   /note="Framework-4"
FT   DISULFID        23..92
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT   NON_TER         111
FT   STRAND          4..7
FT                   /evidence="ECO:0007829|PDB:1F11"
FT   STRAND          9..14
FT                   /evidence="ECO:0007829|PDB:1F11"
FT   STRAND          19..27
FT                   /evidence="ECO:0007829|PDB:1F11"
FT   STRAND          37..42
FT                   /evidence="ECO:0007829|PDB:1F11"
FT   STRAND          49..53
FT                   /evidence="ECO:0007829|PDB:1F11"
FT   TURN            54..56
FT                   /evidence="ECO:0007829|PDB:1F11"
FT   STRAND          66..71
FT                   /evidence="ECO:0007829|PDB:1F11"
FT   STRAND          74..81
FT                   /evidence="ECO:0007829|PDB:1F11"
FT   HELIX           84..86
FT                   /evidence="ECO:0007829|PDB:1F11"
FT   STRAND          88..94
FT                   /evidence="ECO:0007829|PDB:1F11"
FT   STRAND          96..99
FT                   /evidence="ECO:0007829|PDB:1F11"
FT   STRAND          106..111
FT                   /evidence="ECO:0007829|PDB:1F11"
SQ   SEQUENCE   111 AA;  12002 MW;  7A5FCB586C306D29 CRC64;
     DIVLTQSPAS LAVSLGQRAT ISCKASQSVD YDGDSYMNWY QQKPGQPPKL LIYAASNLES
     GIPARFSGSG SGTDFTLNIH PVEEEDAATY YCQQSNEDPF TFGSGTKLEI K