ID   KV3AE_MOUSE             Reviewed;         111 AA.
AC   P01666;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=Ig kappa chain V-III region PC 7183;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=103003; DOI=10.1038/276785a0;
RA   Weigert M., Gatmaitan L., Loh E., Schilling J., Hood L.E.;
RT   "Rearrangement of genetic information may produce immunoglobulin
RT   diversity.";
RL   Nature 276:785-790(1978).
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DR   PIR; B01937; KVMS83.
DR   PDB; 1F58; X-ray; 2.00 A; L=1-111.
DR   PDB; 2F58; X-ray; 2.80 A; L=1-111.
DR   PDB; 3F58; X-ray; 2.80 A; L=1-111.
DR   PDBsum; 1F58; -.
DR   PDBsum; 2F58; -.
DR   PDBsum; 3F58; -.
DR   AlphaFoldDB; P01666; -.
DR   SMR; P01666; -.
DR   MaxQB; P01666; -.
DR   PRIDE; P01666; -.
DR   EvolutionaryTrace; P01666; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; P01666; protein.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR   GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; IBA:GO_Central.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Adaptive immunity; Direct protein sequencing; Disulfide bond;
KW   Immunity; Immunoglobulin; Reference proteome.
FT   CHAIN           1..>111
FT                   /note="Ig kappa chain V-III region PC 7183"
FT                   /id="PRO_0000059788"
FT   REGION          1..23
FT                   /note="Framework-1"
FT   REGION          24..38
FT                   /note="Complementarity-determining-1"
FT   REGION          39..53
FT                   /note="Framework-2"
FT   REGION          54..60
FT                   /note="Complementarity-determining-2"
FT   REGION          61..92
FT                   /note="Framework-3"
FT   REGION          93..101
FT                   /note="Complementarity-determining-3"
FT   REGION          102..111
FT                   /note="Framework-4"
FT   DISULFID        23..92
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT   NON_TER         111
FT   STRAND          4..7
FT                   /evidence="ECO:0007829|PDB:1F58"
FT   STRAND          9..13
FT                   /evidence="ECO:0007829|PDB:1F58"
FT   STRAND          19..27
FT                   /evidence="ECO:0007829|PDB:1F58"
FT   STRAND          37..42
FT                   /evidence="ECO:0007829|PDB:1F58"
FT   STRAND          49..53
FT                   /evidence="ECO:0007829|PDB:1F58"
FT   TURN            54..56
FT                   /evidence="ECO:0007829|PDB:1F58"
FT   STRAND          66..71
FT                   /evidence="ECO:0007829|PDB:1F58"
FT   STRAND          74..81
FT                   /evidence="ECO:0007829|PDB:1F58"
FT   HELIX           84..86
FT                   /evidence="ECO:0007829|PDB:1F58"
FT   STRAND          88..94
FT                   /evidence="ECO:0007829|PDB:1F58"
FT   STRAND          96..99
FT                   /evidence="ECO:0007829|PDB:1F58"
FT   STRAND          106..110
FT                   /evidence="ECO:0007829|PDB:1F58"
SQ   SEQUENCE   111 AA;  11952 MW;  2058BB50CE306D31 CRC64;
     DIVLTQSPAS LAVSLGQRAT ISCKASQSVD YDGDSYMNWY QQKPGQPPKL LIYAASNLES
     GIPARFSGSG SGTDFTLNIH PVEEEDAATY YCQQSNEDPL TFGAGTKLEL K