ID   KV4A1_MOUSE             Reviewed;         129 AA.
AC   P01680;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   23-FEB-2022, entry version 106.
DE   RecName: Full=Ig kappa chain V-IV region S107B;
DE   Flags: Precursor;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=6799208; DOI=10.1016/0092-8674(81)90033-7;
RA   Kwan S.-P., Max E.E., Seidman J.G., Leder P., Scharff M.D.;
RT   "Two kappa immunoglobulin genes are expressed in the myeloma S107.";
RL   Cell 26:57-66(1981).
CC   -!- MISCELLANEOUS: This protein, in which there is a deletion of two amino
CC       acids at the V-J recombination site (after position 118), is
CC       synthesized but not secreted in cells that express and secrete the
CC       normal kappa chain S107.
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DR   EMBL; J00577; AAA38780.1; -; Genomic_DNA.
DR   EMBL; V00780; CAA24157.1; -; Genomic_DNA.
DR   PIR; A01943; KVMS7B.
DR   CPTAC; non-CPTAC-3652; -.
DR   MaxQB; P01680; -.
DR   PeptideAtlas; P01680; -.
DR   PRIDE; P01680; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; P01680; protein.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR   GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; IBA:GO_Central.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   4: Predicted;
KW   Adaptive immunity; Disulfide bond; Immunity; Immunoglobulin;
KW   Reference proteome; Signal.
FT   SIGNAL          1..22
FT   CHAIN           23..129
FT                   /note="Ig kappa chain V-IV region S107B"
FT                   /id="PRO_0000015188"
FT   REGION          23..45
FT                   /note="Framework-1"
FT   REGION          46..57
FT                   /note="Complementarity-determining-1"
FT   REGION          58..72
FT                   /note="Framework-2"
FT   REGION          73..79
FT                   /note="Complementarity-determining-2"
FT   REGION          80..111
FT                   /note="Framework-3"
FT   REGION          112..118
FT                   /note="Complementarity-determining-3"
FT   REGION          119..128
FT                   /note="Framework-4"
FT   DISULFID        45..111
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT   NON_TER         129
SQ   SEQUENCE   129 AA;  13834 MW;  E4BB73072DCF6BE4 CRC64;
     MDLQVQIIXF LLISVTVIMS RGENVLTQSP AIMAASLGQK VTMTCSASSS VSSSYLHWYQ
     QKSGASPKPL IHRTSNLASG VPARFSGSGS GTSYSLTISS VEAEDDATYY CQQWSGYPFG
     SGTKLEIKR