ID   KV5A4_MOUSE             Reviewed;         108 AA.
AC   P01636;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 113.
DE   RecName: Full=Ig kappa chain V-V region MOPC 149;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   STRAIN=BALB/cJ;
RX   PubMed=6795447; DOI=10.1016/0161-5890(80)90176-5;
RA   Appella E., Alvarez V.L.;
RT   "Amino acid sequence of the variable region of M149 mouse myeloma light
RT   chain: comparison with the nucleotide sequence of K2 and K3 clones.";
RL   Mol. Immunol. 17:1507-1513(1980).
CC   -!- MISCELLANEOUS: This chain was isolated from a myeloma protein.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   PIR; A01919; KVMS49.
DR   PIR; B47329; B47329.
DR   PDB; 1AR1; X-ray; 2.70 A; C=-.
DR   PDB; 1MQK; X-ray; 1.28 A; L=8-108.
DR   PDB; 3EHB; X-ray; 2.32 A; D=8-108.
DR   PDB; 3HB3; X-ray; 2.25 A; D=8-108.
DR   PDBsum; 1AR1; -.
DR   PDBsum; 1MQK; -.
DR   PDBsum; 3EHB; -.
DR   PDBsum; 3HB3; -.
DR   AlphaFoldDB; P01636; -.
DR   SMR; P01636; -.
DR   IntAct; P01636; 1.
DR   CPTAC; non-CPTAC-3526; -.
DR   MaxQB; P01636; -.
DR   PeptideAtlas; P01636; -.
DR   PRIDE; P01636; -.
DR   EvolutionaryTrace; P01636; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; P01636; protein.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR   GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; IBA:GO_Central.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Adaptive immunity; Direct protein sequencing; Disulfide bond;
KW   Immunity; Immunoglobulin; Reference proteome.
FT   CHAIN           1..>108
FT                   /note="Ig kappa chain V-V region MOPC 149"
FT                   /id="PRO_0000059797"
FT   REGION          1..23
FT                   /note="Framework-1"
FT   REGION          24..34
FT                   /note="Complementarity-determining-1"
FT   REGION          35..49
FT                   /note="Framework-2"
FT   REGION          50..56
FT                   /note="Complementarity-determining-2"
FT   REGION          57..88
FT                   /note="Framework-3"
FT   REGION          89..97
FT                   /note="Complementarity-determining-3"
FT   REGION          98..108
FT                   /note="Framework-4"
FT   DISULFID        23..88
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT   NON_TER         108
FT   STRAND          4..7
FT                   /evidence="ECO:0007829|PDB:1MQK"
FT   STRAND          9..13
FT                   /evidence="ECO:0007829|PDB:1MQK"
FT   STRAND          19..27
FT                   /evidence="ECO:0007829|PDB:1MQK"
FT   STRAND          33..38
FT                   /evidence="ECO:0007829|PDB:1MQK"
FT   STRAND          45..49
FT                   /evidence="ECO:0007829|PDB:1MQK"
FT   TURN            50..52
FT                   /evidence="ECO:0007829|PDB:1MQK"
FT   STRAND          62..67
FT                   /evidence="ECO:0007829|PDB:1MQK"
FT   STRAND          70..77
FT                   /evidence="ECO:0007829|PDB:1MQK"
FT   HELIX           80..82
FT                   /evidence="ECO:0007829|PDB:1MQK"
FT   STRAND          84..90
FT                   /evidence="ECO:0007829|PDB:1MQK"
FT   STRAND          92..95
FT                   /evidence="ECO:0007829|PDB:1MQK"
FT   STRAND          102..106
FT                   /evidence="ECO:0007829|PDB:1MQK"
SQ   SEQUENCE   108 AA;  12030 MW;  0B5244D2B410D84C CRC64;
     DIQMTQSPDY LSASVGETVT ITCRASENIY SYLAWYQQKQ GKSPQLLVYD AKTLVEGVPS
     RFSGSGSGTQ FSLKINSLQP EDFGSYYCQH HYGIPFTFGS GTKLEIKR