KV5A9_MOUSE
ID KV5A9_MOUSE Reviewed; 115 AA.
AC P01642;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 21-JUL-1986, sequence version 1.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=Ig kappa chain V-V region L7;
DE Flags: Precursor; Fragment;
GN Name=Gm10881;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RX PubMed=6264318; DOI=10.1038/291668a0;
RA Pech M., Hochtl J., Schnell H., Zachau H.G.;
RT "Differences between germ-line and rearranged immunoglobulin V kappa coding
RT sequences suggest a localized mutation mechanism.";
RL Nature 291:668-670(1981).
CC -!- MISCELLANEOUS: There appears to be two possible splice junctions at the
CC 3' end of the intron. The alternate would code for a protein lacking
CC residues 17-19.
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DR PIR; A01925; KVMSL7.
DR PDB; 1C08; X-ray; 2.30 A; A=21-115.
DR PDB; 1IC4; X-ray; 2.50 A; L=21-115.
DR PDB; 1IC5; X-ray; 2.30 A; L=21-115.
DR PDB; 1IC7; X-ray; 2.10 A; L=21-115.
DR PDB; 1J1O; X-ray; 1.80 A; L=21-115.
DR PDB; 1J1P; X-ray; 1.80 A; L=21-115.
DR PDB; 1J1X; X-ray; 1.80 A; L=21-115.
DR PDB; 2OZ4; X-ray; 2.70 A; L=21-115.
DR PDB; 4CKD; EM; 13.00 A; L/M/N/O=21-115.
DR PDBsum; 1C08; -.
DR PDBsum; 1IC4; -.
DR PDBsum; 1IC5; -.
DR PDBsum; 1IC7; -.
DR PDBsum; 1J1O; -.
DR PDBsum; 1J1P; -.
DR PDBsum; 1J1X; -.
DR PDBsum; 2OZ4; -.
DR PDBsum; 4CKD; -.
DR AlphaFoldDB; P01642; -.
DR SMR; P01642; -.
DR CPTAC; non-CPTAC-3522; -.
DR MaxQB; P01642; -.
DR PeptideAtlas; P01642; -.
DR PRIDE; P01642; -.
DR Ensembl; ENSMUST00000103364; ENSMUSP00000100165; ENSMUSG00000076563.
DR MGI; MGI:3642817; Gm10881.
DR VEuPathDB; HostDB:ENSMUSG00000076563; -.
DR GeneTree; ENSGT00940000163546; -.
DR HOGENOM; CLU_077975_4_1_1; -.
DR InParanoid; P01642; -.
DR OMA; QDYSCYP; -.
DR ChiTaRS; Igkv5-48; mouse.
DR EvolutionaryTrace; P01642; -.
DR Proteomes; UP000000589; Chromosome 6.
DR RNAct; P01642; protein.
DR Bgee; ENSMUSG00000076563; Expressed in jejunum and 22 other tissues.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR GO; GO:0006955; P:immune response; IBA:GO_Central.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00408; IGc2; 1.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; SSF48726; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Adaptive immunity; Disulfide bond; Immunity; Immunoglobulin;
KW Reference proteome; Signal.
FT SIGNAL 1..20
FT CHAIN 21..>115
FT /note="Ig kappa chain V-V region L7"
FT /id="PRO_0000015196"
FT REGION 21..43
FT /note="Framework-1"
FT REGION 44..54
FT /note="Complementarity-determining-1"
FT REGION 55..69
FT /note="Framework-2"
FT REGION 70..76
FT /note="Complementarity-determining-2"
FT REGION 77..108
FT /note="Framework-3"
FT REGION 109..>115
FT /note="Complementarity-determining-3"
FT DISULFID 43..108
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT NON_TER 115
FT STRAND 24..27
FT /evidence="ECO:0007829|PDB:1J1O"
FT STRAND 29..33
FT /evidence="ECO:0007829|PDB:1J1O"
FT STRAND 39..47
FT /evidence="ECO:0007829|PDB:1J1O"
FT STRAND 53..58
FT /evidence="ECO:0007829|PDB:1J1O"
FT STRAND 65..69
FT /evidence="ECO:0007829|PDB:1J1O"
FT TURN 70..72
FT /evidence="ECO:0007829|PDB:1J1O"
FT STRAND 82..87
FT /evidence="ECO:0007829|PDB:1J1O"
FT STRAND 90..97
FT /evidence="ECO:0007829|PDB:1J1O"
FT HELIX 100..102
FT /evidence="ECO:0007829|PDB:1J1O"
FT STRAND 104..110
FT /evidence="ECO:0007829|PDB:1J1O"
FT STRAND 112..115
FT /evidence="ECO:0007829|PDB:1J1O"
SQ SEQUENCE 115 AA; 12615 MW; C17BEC758C577E00 CRC64;
MVSTPQFLVF LLFWIPASRG DILLTQSPAI LSVSPGERVS FSCRASQSIG TSIHWYQQRT
NGSPRLLIKY ASESISGIPS RFSGSGSGTD FTLSINSVES EDIADYYCQQ SNSWP
