KV5AF_MOUSE
ID KV5AF_MOUSE Reviewed; 108 AA.
AC P01648;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 21-JUL-1986, sequence version 1.
DT 25-MAY-2022, entry version 98.
DE RecName: Full=Ig kappa chain V-V region HP 91A3;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP PROTEIN SEQUENCE.
RC STRAIN=A/J;
RX PubMed=6801658; DOI=10.1073/pnas.78.12.7679;
RA Siegelman M., Capra J.D.;
RT "Complete amino acid sequence of light chain variable regions derived from
RT five monoclonal anti-p-azophenylarsonate antibodies differing with respect
RT to a crossreactive idiotype.";
RL Proc. Natl. Acad. Sci. U.S.A. 78:7679-7683(1981).
CC -!- MISCELLANEOUS: Anti-arsonate hybridoma protein.
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DR PDB; 1JFQ; X-ray; 1.90 A; L=1-108.
DR PDBsum; 1JFQ; -.
DR AlphaFoldDB; P01648; -.
DR SMR; P01648; -.
DR MaxQB; P01648; -.
DR PeptideAtlas; P01648; -.
DR PRIDE; P01648; -.
DR EvolutionaryTrace; P01648; -.
DR Proteomes; UP000000589; Unplaced.
DR RNAct; P01648; protein.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR GO; GO:0006955; P:immune response; IBA:GO_Central.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; SSF48726; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Adaptive immunity; Direct protein sequencing; Disulfide bond;
KW Immunity; Immunoglobulin; Reference proteome.
FT CHAIN 1..>108
FT /note="Ig kappa chain V-V region HP 91A3"
FT /id="PRO_0000059803"
FT REGION 1..23
FT /note="Framework-1"
FT REGION 24..34
FT /note="Complementarity-determining-1"
FT REGION 35..49
FT /note="Framework-2"
FT REGION 50..56
FT /note="Complementarity-determining-2"
FT REGION 57..88
FT /note="Framework-3"
FT REGION 89..97
FT /note="Complementarity-determining-3"
FT REGION 98..108
FT /note="Framework-4"
FT DISULFID 23..88
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT NON_TER 108
FT STRAND 4..7
FT /evidence="ECO:0007829|PDB:1JFQ"
FT STRAND 9..13
FT /evidence="ECO:0007829|PDB:1JFQ"
FT STRAND 19..27
FT /evidence="ECO:0007829|PDB:1JFQ"
FT STRAND 33..38
FT /evidence="ECO:0007829|PDB:1JFQ"
FT STRAND 44..49
FT /evidence="ECO:0007829|PDB:1JFQ"
FT TURN 50..52
FT /evidence="ECO:0007829|PDB:1JFQ"
FT STRAND 62..67
FT /evidence="ECO:0007829|PDB:1JFQ"
FT STRAND 70..77
FT /evidence="ECO:0007829|PDB:1JFQ"
FT HELIX 80..82
FT /evidence="ECO:0007829|PDB:1JFQ"
FT STRAND 84..90
FT /evidence="ECO:0007829|PDB:1JFQ"
FT STRAND 92..95
FT /evidence="ECO:0007829|PDB:1JFQ"
FT STRAND 102..106
FT /evidence="ECO:0007829|PDB:1JFQ"
SQ SEQUENCE 108 AA; 11961 MW; D52EDA5E9A45291C CRC64;
DIQMTQTPSS LSASLGDRVT ISCRASQDIN NYLNWYRQKP DGTVKLLIYY TSRLHSGVPS
RFSGSGSGTD YSLTISNLEQ EDISTYFCQQ GNALPRTFGG GTKLEIKR
