ID   KV5AG_MOUSE             Reviewed;         108 AA.
AC   P01649;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Ig kappa chain V-V regions;
DE   AltName: Full=Anti-arsonate antibodies;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   STRAIN=A/J;
RX   PubMed=70482;
RA   Capra J.D., Tung A.S., Nisonoff A.;
RT   "Structural studies on induced antibodies with defined idiotypic
RT   specificities. V. The complete amino acid sequence of the light chain
RT   variable regions of anti-p-azophenylarsonate antibodies from A/J mice
RT   bearing a cross-reactive idiotype.";
RL   J. Immunol. 119:993-999(1977).
CC   -!- MISCELLANEOUS: The mixture sequenced contained at least two or three
CC       different light chains. Peptides containing the following substitutions
CC       were also isolated: Val-3, Ile-10, and Leu-12; Leu-22; Phe-36, Glu-42,
CC       and Ala-43; Thr-63 and Arg-68; Ser-76, Ser-77, Val-78, Ala-80, and Asp-
CC       85; and Gln-100 and Arg-107.
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DR   PIR; A01928; KVMSAA.
DR   AlphaFoldDB; P01649; -.
DR   SMR; P01649; -.
DR   MaxQB; P01649; -.
DR   PRIDE; P01649; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; P01649; protein.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR   GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; IBA:GO_Central.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   Adaptive immunity; Direct protein sequencing; Disulfide bond; Immunity;
KW   Immunoglobulin; Reference proteome.
FT   CHAIN           1..>108
FT                   /note="Ig kappa chain V-V regions"
FT                   /id="PRO_0000059804"
FT   REGION          1..23
FT                   /note="Framework-1"
FT   REGION          24..34
FT                   /note="Complementarity-determining-1"
FT   REGION          35..49
FT                   /note="Framework-2"
FT   REGION          50..56
FT                   /note="Complementarity-determining-2"
FT   REGION          57..88
FT                   /note="Framework-3"
FT   REGION          89..97
FT                   /note="Complementarity-determining-3"
FT   REGION          98..108
FT                   /note="Framework-4"
FT   DISULFID        23..88
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT   NON_TER         108
SQ   SEQUENCE   108 AA;  12057 MW;  AE2861E6AAC09DD2 CRC64;
     DIQMTQTPSS LSASLGDRVS ISCRASQDLS QYLFWYQQKP GQPPKLLIYR VSRLTNGVPD
     RFSGSGSGTD FTLTIDPMEE DDTATYFCQQ SRLIPRTFGG GTKLEIKR