KV5AM_MOUSE
ID KV5AM_MOUSE Reviewed; 108 AA.
AC P04946;
DT 13-AUG-1987, integrated into UniProtKB/Swiss-Prot.
DT 13-AUG-1987, sequence version 1.
DT 25-MAY-2022, entry version 92.
DE RecName: Full=Ig kappa chain V-V region NQ5-89.4;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=6877353; DOI=10.1038/304320a0;
RA Kaartinen M., Griffiths G.M., Markham A.F., Milstein C.;
RT "mRNA sequences define an unusually restricted IgG response to 2-
RT phenyloxazolone and its early diversification.";
RL Nature 304:320-324(1983).
CC -!- FUNCTION: Anti-2-phenyl oxazolone (PHOX) Antibody.
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DR EMBL; K00745; AAA38690.1; -; mRNA.
DR MaxQB; P04946; -.
DR PRIDE; P04946; -.
DR Proteomes; UP000000589; Unplaced.
DR RNAct; P04946; protein.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR GO; GO:0006955; P:immune response; IBA:GO_Central.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; SSF48726; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 2: Evidence at transcript level;
KW Adaptive immunity; Disulfide bond; Hybridoma; Immunity; Immunoglobulin;
KW Reference proteome.
FT CHAIN 1..>108
FT /note="Ig kappa chain V-V region NQ5-89.4"
FT /id="PRO_0000059809"
FT REGION 1..23
FT /note="Framework-1"
FT REGION 24..34
FT /note="Complementarity-determining-1"
FT REGION 35..49
FT /note="Framework-2"
FT REGION 50..56
FT /note="Complementarity-determining-2"
FT REGION 57..88
FT /note="Framework-3"
FT REGION 89..97
FT /note="Complementarity-determining-3"
FT REGION 98..107
FT /note="Framework-4"
FT DISULFID 23..88
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT NON_TER 108
SQ SEQUENCE 108 AA; 11870 MW; DB2C885920DC6DDD CRC64;
DIQMTQTTSS LSASLGHRVT ITCSASQDIS NYLNWYQQKP DGTVKLLIYY TSRLHSGVPS
RFSGSGSATD YSLTITNLQQ EDXATYXCQQ GNTLPYTFGG GTKLXIKR