ID   KV6A1_MOUSE             Reviewed;         107 AA.
AC   P01675;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=Ig kappa chain V-VI region XRPC 44;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=103573; DOI=10.1021/bi00618a035;
RA   Rao D.N., Rudikoff S., Potter M.;
RT   "Kappa chain variable regions from three galactan binding myeloma
RT   proteins.";
RL   Biochemistry 17:5555-5559(1978).
RN   [2]
RP   PROTEIN SEQUENCE.
RX   PubMed=6776525; DOI=10.1073/pnas.77.7.4270;
RA   Rudikoff S., Rao D.N., Glaudemans C.P.J., Potter M.;
RT   "Kappa chain joining segments and structural diversity of antibody
RT   combining sites.";
RL   Proc. Natl. Acad. Sci. U.S.A. 77:4270-4274(1980).
CC   -!- MISCELLANEOUS: This chain was isolated from a myeloma protein that bind
CC       galactan.
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DR   PIR; A90420; KVMSX4.
DR   PDB; 3BT2; X-ray; 2.50 A; L=1-107.
DR   PDBsum; 3BT2; -.
DR   AlphaFoldDB; P01675; -.
DR   SMR; P01675; -.
DR   MaxQB; P01675; -.
DR   PeptideAtlas; P01675; -.
DR   PRIDE; P01675; -.
DR   EvolutionaryTrace; P01675; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; P01675; protein.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR   GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; IBA:GO_Central.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Adaptive immunity; Direct protein sequencing; Disulfide bond;
KW   Immunity; Immunoglobulin; Reference proteome.
FT   CHAIN           1..>107
FT                   /note="Ig kappa chain V-VI region XRPC 44"
FT                   /id="PRO_0000059810"
FT   REGION          1..23
FT                   /note="Framework-1"
FT   REGION          24..33
FT                   /note="Complementarity-determining-1"
FT   REGION          34..48
FT                   /note="Framework-2"
FT   REGION          49..55
FT                   /note="Complementarity-determining-2"
FT   REGION          56..87
FT                   /note="Framework-3"
FT   REGION          88..96
FT                   /note="Complementarity-determining-3"
FT   REGION          97..106
FT                   /note="Framework-4"
FT   DISULFID        23..87
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT   CONFLICT        95
FT                   /note="W -> I (in Ref. 2; AA sequence)"
FT                   /evidence="ECO:0000305"
FT   NON_TER         107
SQ   SEQUENCE   107 AA;  11627 MW;  27A2D022BC0A34D7 CRC64;
     EIVLTQSPAI TAASLGQKVT ITCSASSSVS YMHWYQQKSG TSPKPWIYEI SKLASGVPAR
     FSGSGSGTSY SLTISSMEAE DAAIYYCQQW NYPLWTFGGG TKLEIKR