KV6A5_MOUSE
ID KV6A5_MOUSE Reviewed; 107 AA.
AC P01679;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 21-JUL-1986, sequence version 1.
DT 25-MAY-2022, entry version 107.
DE RecName: Full=Ig kappa chain V-VI region J539;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP PROTEIN SEQUENCE.
RX PubMed=6776525; DOI=10.1073/pnas.77.7.4270;
RA Rudikoff S., Rao D.N., Glaudemans C.P.J., Potter M.;
RT "Kappa chain joining segments and structural diversity of antibody
RT combining sites.";
RL Proc. Natl. Acad. Sci. U.S.A. 77:4270-4274(1980).
RN [2]
RP X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS).
RX PubMed=3449853; DOI=10.1002/prot.340010112;
RA Suh S.W., Bhat T.N., Navia M.A., Cohen G.H., Rao D.N., Rudikoff S.,
RA Davies D.R.;
RT "The galactan-binding immunoglobulin Fab J539: an X-ray diffraction study
RT at 2.6-A resolution.";
RL Proteins 1:74-80(1986).
CC -!- MISCELLANEOUS: This chain was isolated from a myeloma protein that bind
CC galactan.
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DR PIR; A01942; KVMSJ5.
DR PDB; 2FBJ; X-ray; 1.95 A; L=1-107.
DR PDBsum; 2FBJ; -.
DR AlphaFoldDB; P01679; -.
DR SMR; P01679; -.
DR MaxQB; P01679; -.
DR PRIDE; P01679; -.
DR EvolutionaryTrace; P01679; -.
DR Proteomes; UP000000589; Unplaced.
DR RNAct; P01679; protein.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR GO; GO:0006955; P:immune response; IBA:GO_Central.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; SSF48726; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Adaptive immunity; Direct protein sequencing; Disulfide bond;
KW Immunity; Immunoglobulin; Reference proteome.
FT CHAIN 1..>107
FT /note="Ig kappa chain V-VI region J539"
FT /id="PRO_0000059814"
FT REGION 1..23
FT /note="Framework-1"
FT REGION 24..33
FT /note="Complementarity-determining-1"
FT REGION 34..48
FT /note="Framework-2"
FT REGION 49..55
FT /note="Complementarity-determining-2"
FT REGION 56..87
FT /note="Framework-3"
FT REGION 88..96
FT /note="Complementarity-determining-3"
FT REGION 97..106
FT /note="Framework-4"
FT DISULFID 23..87
FT NON_TER 107
FT STRAND 4..14
FT /evidence="ECO:0007829|PDB:2FBJ"
FT STRAND 19..27
FT /evidence="ECO:0007829|PDB:2FBJ"
FT STRAND 30..37
FT /evidence="ECO:0007829|PDB:2FBJ"
FT STRAND 44..48
FT /evidence="ECO:0007829|PDB:2FBJ"
FT TURN 49..51
FT /evidence="ECO:0007829|PDB:2FBJ"
FT STRAND 61..66
FT /evidence="ECO:0007829|PDB:2FBJ"
FT STRAND 69..76
FT /evidence="ECO:0007829|PDB:2FBJ"
FT HELIX 79..81
FT /evidence="ECO:0007829|PDB:2FBJ"
FT STRAND 83..91
FT /evidence="ECO:0007829|PDB:2FBJ"
FT STRAND 101..106
FT /evidence="ECO:0007829|PDB:2FBJ"
SQ SEQUENCE 107 AA; 11502 MW; EA30C9A3E903979C CRC64;
EIVLTQSPAI TAASLGQKVT ITCSASSSVS SLHWYQQKSG TSPKPWIYEI SKLASGVPAR
FSGSGSGTSY SLTINTMEAE DAAIYYCQQW TYPLITFGAG TKLELKR
