ID   KXD1_CANGA              Reviewed;         203 AA.
AC   Q6FS55;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit KXD1;
DE            Short=BLOC-1 subunit KXD1;
DE   AltName: Full=KxDL homolog;
GN   Name=KXD1; OrderedLocusNames=CAGL0H03355g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Component of the biogenesis of lysosome-related organelles
CC       complex-1 (BLOC-1) involved in endosomal cargo sorting. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the biogenesis of lysosome-related organelles
CC       complex-1 (BLOC-1). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endosome {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the KXD1 family. {ECO:0000305}.
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DR   EMBL; CR380954; CAG59872.1; -; Genomic_DNA.
DR   RefSeq; XP_446939.1; XM_446939.1.
DR   AlphaFoldDB; Q6FS55; -.
DR   SMR; Q6FS55; -.
DR   STRING; 5478.XP_446939.1; -.
DR   EnsemblFungi; CAG59872; CAG59872; CAGL0H03355g.
DR   GeneID; 2888863; -.
DR   KEGG; cgr:CAGL0H03355g; -.
DR   CGD; CAL0132014; CAGL0H03355g.
DR   VEuPathDB; FungiDB:CAGL0H03355g; -.
DR   eggNOG; ENOG502S1H5; Eukaryota.
DR   HOGENOM; CLU_099155_0_0_1; -.
DR   InParanoid; Q6FS55; -.
DR   OMA; PIEYNQS; -.
DR   Proteomes; UP000002428; Chromosome H.
DR   GO; GO:0031083; C:BLOC-1 complex; IEA:EnsemblFungi.
DR   GO; GO:0005768; C:endosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0009318; C:exodeoxyribonuclease VII complex; IEA:InterPro.
DR   GO; GO:0008855; F:exodeoxyribonuclease VII activity; IEA:InterPro.
DR   GO; GO:0006308; P:DNA catabolic process; IEA:InterPro.
DR   GO; GO:0007032; P:endosome organization; IEA:EnsemblFungi.
DR   GO; GO:0032880; P:regulation of protein localization; IEA:EnsemblFungi.
DR   InterPro; IPR037004; Exonuc_VII_ssu_sf.
DR   InterPro; IPR019371; Uncharacterised_KxDL.
DR   Pfam; PF10241; KxDL; 1.
DR   SUPFAM; SSF116842; SSF116842; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Endosome; Reference proteome; Transport.
FT   CHAIN           1..203
FT                   /note="Biogenesis of lysosome-related organelles complex 1
FT                   subunit KXD1"
FT                   /id="PRO_0000410667"
FT   REGION          1..62
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          126..178
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        15..29
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   203 AA;  22824 MW;  17EA12EE4659FFC4 CRC64;
     MSDEIEDRPR TRSRTPSVDT QSYTINEEAH HIITDSDSSS SENEDGEGNE TNSSDDSSES
     GSVERFLDEI VPTTSTSFIP NDTPDPATLF DITEYIFDSI VQSTNACDFS EAFALQAKTS
     AVINSKSMEL KNLIEQTKVR LPELQAKFKN GTQTLRTIRK NLDNAKSRIQ VMNDVLQTDY
     PIEFNQARDK ILERTLDSDE EVI