KXD1_YEAS6
ID KXD1_YEAS6 Reviewed; 218 AA.
AC B5VIP5;
DT 28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT 25-NOV-2008, sequence version 1.
DT 25-MAY-2022, entry version 31.
DE RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit KXD1;
DE Short=BLOC-1 subunit KXD1;
DE AltName: Full=KxDL homolog;
GN Name=KXD1; ORFNames=AWRI1631_71720;
OS Saccharomyces cerevisiae (strain AWRI1631) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=545124;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AWRI1631;
RX PubMed=18778279; DOI=10.1111/j.1567-1364.2008.00434.x;
RA Borneman A.R., Forgan A.H., Pretorius I.S., Chambers P.J.;
RT "Comparative genome analysis of a Saccharomyces cerevisiae wine strain.";
RL FEMS Yeast Res. 8:1185-1195(2008).
CC -!- FUNCTION: Component of the biogenesis of lysosome-related organelles
CC complex-1 (BLOC-1) involved in endosomal cargo sorting. {ECO:0000250}.
CC -!- SUBUNIT: Component of the biogenesis of lysosome-related organelles
CC complex-1 (BLOC-1) composed of at least BLI1, BLS1, CNL1, KXD1, SNN1
CC and VAB2. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Endosome {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the KXD1 family. {ECO:0000305}.
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DR EMBL; ABSV01000882; EDZ72197.1; -; Genomic_DNA.
DR AlphaFoldDB; B5VIP5; -.
DR SMR; B5VIP5; -.
DR Proteomes; UP000008988; Unassembled WGS sequence.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-SubCell.
DR InterPro; IPR019371; Uncharacterised_KxDL.
DR Pfam; PF10241; KxDL; 1.
PE 3: Inferred from homology;
KW Coiled coil; Endosome; Transport.
FT CHAIN 1..218
FT /note="Biogenesis of lysosome-related organelles complex 1
FT subunit KXD1"
FT /id="PRO_0000410671"
FT REGION 1..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 142..192
FT /evidence="ECO:0000255"
FT COMPBIAS 16..65
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 218 AA; 24442 MW; 61541771FBEC8F8C CRC64;
MVTGISEEND DEETFSAVHS STPSINSQSY AIPITEEMSS SFHDSISTTS NSSGSFDSDG
SNVSDVVEQN EMDNESNVDE DLFLDNDIPQ SSNLLPTDAQ DPGPIFDVSR YIFDSLKQSI
DSADFSEALS LQTKTSAVIN SKSLELKQYI DEMKSRLTQL QEKFENGEAT SKKIKRDLET
SRKNIDYLNA ALRVDFPIEF NQAREKILER RLNEDHDC