ID   KXD1_YEAS8              Reviewed;         218 AA.
AC   C8Z8G8;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   03-NOV-2009, sequence version 1.
DT   25-MAY-2022, entry version 31.
DE   RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit KXD1;
DE            Short=BLOC-1 subunit KXD1;
DE   AltName: Full=KxDL homolog;
GN   Name=KXD1; ORFNames=EC1118_1G1_2102g;
OS   Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) (Baker's
OS   yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=643680;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lalvin EC1118 / Prise de mousse;
RX   PubMed=19805302; DOI=10.1073/pnas.0904673106;
RA   Novo M., Bigey F., Beyne E., Galeote V., Gavory F., Mallet S., Cambon B.,
RA   Legras J.-L., Wincker P., Casaregola S., Dequin S.;
RT   "Eukaryote-to-eukaryote gene transfer events revealed by the genome
RT   sequence of the wine yeast Saccharomyces cerevisiae EC1118.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:16333-16338(2009).
CC   -!- FUNCTION: Component of the biogenesis of lysosome-related organelles
CC       complex-1 (BLOC-1) involved in endosomal cargo sorting. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the biogenesis of lysosome-related organelles
CC       complex-1 (BLOC-1) composed of at least BLI1, BLS1, CNL1, KXD1, SNN1
CC       and VAB2. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endosome {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the KXD1 family. {ECO:0000305}.
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DR   EMBL; FN393070; CAY79684.1; -; Genomic_DNA.
DR   AlphaFoldDB; C8Z8G8; -.
DR   SMR; C8Z8G8; -.
DR   EnsemblFungi; CAY79684; CAY79684; EC1118_1G1_2102g.
DR   HOGENOM; CLU_099155_0_0_1; -.
DR   Proteomes; UP000000286; Chromosome VII, Scaffold EC1118_1G1.
DR   GO; GO:0005768; C:endosome; IEA:UniProtKB-SubCell.
DR   InterPro; IPR019371; Uncharacterised_KxDL.
DR   Pfam; PF10241; KxDL; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Endosome; Transport.
FT   CHAIN           1..218
FT                   /note="Biogenesis of lysosome-related organelles complex 1
FT                   subunit KXD1"
FT                   /id="PRO_0000410673"
FT   REGION          1..65
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          142..192
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        16..65
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   218 AA;  24442 MW;  61541771FBEC8F8C CRC64;
     MVTGISEEND DEETFSAVHS STPSINSQSY AIPITEEMSS SFHDSISTTS NSSGSFDSDG
     SNVSDVVEQN EMDNESNVDE DLFLDNDIPQ SSNLLPTDAQ DPGPIFDVSR YIFDSLKQSI
     DSADFSEALS LQTKTSAVIN SKSLELKQYI DEMKSRLTQL QEKFENGEAT SKKIKRDLET
     SRKNIDYLNA ALRVDFPIEF NQAREKILER RLNEDHDC