KXD1_ZYGRC
ID KXD1_ZYGRC Reviewed; 195 AA.
AC C5E000;
DT 28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 44.
DE RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit KXD1;
DE Short=BLOC-1 subunit KXD1;
DE AltName: Full=KxDL homolog;
GN Name=KXD1; OrderedLocusNames=ZYRO0G08536g;
OS Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568
OS / NRRL Y-229) (Candida mogii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Zygosaccharomyces.
OX NCBI_TaxID=559307;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 2623 / CBS 732 / BCRC 21506 / NBRC 1130 / NCYC 568 / NRRL
RC Y-229;
RX PubMed=19525356; DOI=10.1101/gr.091546.109;
RG The Genolevures Consortium;
RA Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT "Comparative genomics of protoploid Saccharomycetaceae.";
RL Genome Res. 19:1696-1709(2009).
CC -!- FUNCTION: Component of the biogenesis of lysosome-related organelles
CC complex-1 (BLOC-1) involved in endosomal cargo sorting. {ECO:0000250}.
CC -!- SUBUNIT: Component of the biogenesis of lysosome-related organelles
CC complex-1 (BLOC-1). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Endosome {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the KXD1 family. {ECO:0000305}.
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DR EMBL; CU928179; CAR29434.1; -; Genomic_DNA.
DR RefSeq; XP_002498367.1; XM_002498322.1.
DR AlphaFoldDB; C5E000; -.
DR SMR; C5E000; -.
DR STRING; 559307.C5E000; -.
DR EnsemblFungi; CAR29434; CAR29434; ZYRO0G08536g.
DR GeneID; 8206170; -.
DR KEGG; zro:ZYRO0G08536g; -.
DR HOGENOM; CLU_099155_0_0_1; -.
DR InParanoid; C5E000; -.
DR Proteomes; UP000008536; Chromosome G.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-SubCell.
DR InterPro; IPR019371; Uncharacterised_KxDL.
DR Pfam; PF10241; KxDL; 1.
PE 3: Inferred from homology;
KW Endosome; Reference proteome; Transport.
FT CHAIN 1..195
FT /note="Biogenesis of lysosome-related organelles complex 1
FT subunit KXD1"
FT /id="PRO_0000410679"
FT REGION 1..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..29
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 195 AA; 22018 MW; EB621BA6F2ADB5F8 CRC64;
MDDSSSEARA GIENDTTVRS RSPSVDSQSY AIPMPEEIEE QLSEESSSFD DSNSVESNED
QILGRALPES GQHAFSQDSQ EFEPMLDVSK HIFDSLMQAI DSADFSEAIS LQTKTSAVIN
SKSTELKQLI DETKVRFSQF KERFEKGSLT AKNIRGNLRY SKDKIEKINA LVRTSYPIEF
NEAREKILER PLDDH