ID   KXDL1_DANRE             Reviewed;         182 AA.
AC   Q6DBR9;
DT   24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=KxDL motif-containing protein 1;
GN   Name=kxd1; ORFNames=zgc:91862;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: As part of a BORC-like complex may play a role in lysosomes
CC       movement and localization at the cell periphery. Associated with the
CC       cytosolic face of lysosomes, this complex may couple lysosomes to
CC       microtubule plus-end-directed kinesin motor. May also be involved in
CC       the biogenesis of lysosome-related organelles such as melanosomes.
CC       {ECO:0000250|UniProtKB:Q80XH1, ECO:0000250|UniProtKB:Q9BQD3}.
CC   -!- SUBUNIT: Associates with the BLOC-1 complex.
CC       {ECO:0000250|UniProtKB:Q80XH1}.
CC   -!- SUBCELLULAR LOCATION: Lysosome membrane {ECO:0000250|UniProtKB:Q9BQD3}.
CC   -!- SIMILARITY: Belongs to the KXD1 family. {ECO:0000305}.
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DR   EMBL; BC078391; AAH78391.1; -; mRNA.
DR   RefSeq; NP_001003469.1; NM_001003469.2.
DR   AlphaFoldDB; Q6DBR9; -.
DR   SMR; Q6DBR9; -.
DR   STRING; 7955.ENSDARP00000068138; -.
DR   PaxDb; Q6DBR9; -.
DR   Ensembl; ENSDART00000073648; ENSDARP00000068138; ENSDARG00000051934.
DR   GeneID; 445075; -.
DR   KEGG; dre:445075; -.
DR   CTD; 79036; -.
DR   ZFIN; ZDB-GENE-040801-207; kxd1.
DR   eggNOG; KOG3443; Eukaryota.
DR   GeneTree; ENSGT00530000064192; -.
DR   HOGENOM; CLU_094353_3_0_1; -.
DR   InParanoid; Q6DBR9; -.
DR   OMA; LRMQQMN; -.
DR   OrthoDB; 1612645at2759; -.
DR   PhylomeDB; Q6DBR9; -.
DR   TreeFam; TF319035; -.
DR   PRO; PR:Q6DBR9; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 25.
DR   Bgee; ENSDARG00000051934; Expressed in mature ovarian follicle and 26 other tissues.
DR   GO; GO:0099078; C:BORC complex; ISS:UniProtKB.
DR   GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0032418; P:lysosome localization; ISS:UniProtKB.
DR   GO; GO:0016192; P:vesicle-mediated transport; ISS:UniProtKB.
DR   InterPro; IPR039843; KXD1-like.
DR   InterPro; IPR019371; Uncharacterised_KxDL.
DR   PANTHER; PTHR13511; PTHR13511; 1.
DR   Pfam; PF10241; KxDL; 1.
PE   2: Evidence at transcript level;
KW   Lysosome; Membrane; Reference proteome.
FT   CHAIN           1..182
FT                   /note="KxDL motif-containing protein 1"
FT                   /id="PRO_0000295262"
FT   REGION          124..182
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        124..157
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        158..182
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   182 AA;  20374 MW;  9FF92F8F8DAA1FB7 CRC64;
     MEPTASGIFC NRMLSMVNSE DVNAIIQAQR HMLDRFEKTN EMLINFNGLS NVRLQQMNEH
     FLMHTRTLIE MKKDLDSIFR RIRALKGKVA KQYPEAFSNV SESSNLEDDD DEFDPIPASV
     ATITTTATSE QSTESCDTSP DVISPTISCC SEDPSQEHTD TPTSDSHEQP VLRDEGPDSA
     DI