ID   KXDL1_XENTR             Reviewed;         180 AA.
AC   Q0V9C8;
DT   24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2007, sequence version 2.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=KxDL motif-containing protein 1;
GN   Name=kxd1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=N6; TISSUE=Oviduct;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: As part of a BORC-like complex may play a role in lysosomes
CC       movement and localization at the cell periphery. Associated with the
CC       cytosolic face of lysosomes, this complex may couple lysosomes to
CC       microtubule plus-end-directed kinesin motor. May also be involved in
CC       the biogenesis of lysosome-related organelles such as melanosomes.
CC       {ECO:0000250|UniProtKB:Q80XH1, ECO:0000250|UniProtKB:Q9BQD3}.
CC   -!- SUBUNIT: Associates with the BLOC-1 complex.
CC       {ECO:0000250|UniProtKB:Q80XH1}.
CC   -!- SUBCELLULAR LOCATION: Lysosome membrane {ECO:0000250|UniProtKB:Q9BQD3}.
CC   -!- SIMILARITY: Belongs to the KXD1 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAI21635.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; BC121634; AAI21635.1; ALT_INIT; mRNA.
DR   AlphaFoldDB; Q0V9C8; -.
DR   SMR; Q0V9C8; -.
DR   STRING; 8364.ENSXETP00000030715; -.
DR   PaxDb; Q0V9C8; -.
DR   Ensembl; ENSXETT00000105018; ENSXETP00000096463; ENSXETG00000023203.
DR   eggNOG; KOG3443; Eukaryota.
DR   HOGENOM; CLU_094353_3_0_1; -.
DR   InParanoid; Q0V9C8; -.
DR   OMA; LRMQQMN; -.
DR   TreeFam; TF319035; -.
DR   Proteomes; UP000008143; Genome assembly.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000023203; Expressed in egg cell and 10 other tissues.
DR   GO; GO:0099078; C:BORC complex; ISS:UniProtKB.
DR   GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0032418; P:lysosome localization; ISS:UniProtKB.
DR   GO; GO:0016192; P:vesicle-mediated transport; ISS:UniProtKB.
DR   InterPro; IPR039843; KXD1-like.
DR   InterPro; IPR019371; Uncharacterised_KxDL.
DR   PANTHER; PTHR13511; PTHR13511; 1.
DR   Pfam; PF10241; KxDL; 1.
PE   2: Evidence at transcript level;
KW   Lysosome; Membrane; Reference proteome.
FT   CHAIN           1..180
FT                   /note="KxDL motif-containing protein 1"
FT                   /id="PRO_0000295264"
FT   REGION          126..180
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        126..170
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   180 AA;  20266 MW;  5862C68876A3399F CRC64;
     MAEQVTEATA SGVFCSRILN MVNSEDVNAI ILAQRHMLDR FEKTNEMLLN FNGLSNTRLQ
     QMSDRFAHHT RTLVEMKKDL DIIFRRIRML KGKLAKQYPE SFNNVHESPI LEDDDDFDPT
     PRSAATTIAT SEQSTESCDT SPSIISPAMS QDFEDLSQAP SDTPSVNGQI LTDEEVVHED