L10K_MOUSE
ID L10K_MOUSE Reviewed; 94 AA.
AC Q8R1F0;
DT 31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=Leydig cell tumor 10 kDa protein homolog;
GN Name=D8Ertd738e;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=DBA/2J;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=FVB/N; TISSUE=Colon;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- FUNCTION: May have a potential role in hypercalcemia of malignancy.
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the UPF0390 family. {ECO:0000305}.
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DR EMBL; AK146163; BAE26944.1; -; mRNA.
DR EMBL; AK167785; BAE39817.1; -; mRNA.
DR EMBL; BC024662; AAH24662.1; -; mRNA.
DR CCDS; CCDS40408.1; -.
DR RefSeq; NP_001007572.1; NM_001007571.2.
DR RefSeq; XP_017167984.1; XM_017312495.1.
DR AlphaFoldDB; Q8R1F0; -.
DR BioGRID; 221766; 1.
DR STRING; 10090.ENSMUSP00000019506; -.
DR PhosphoSitePlus; Q8R1F0; -.
DR EPD; Q8R1F0; -.
DR MaxQB; Q8R1F0; -.
DR PaxDb; Q8R1F0; -.
DR PeptideAtlas; Q8R1F0; -.
DR PRIDE; Q8R1F0; -.
DR ProteomicsDB; 263477; -.
DR Antibodypedia; 71794; 39 antibodies from 11 providers.
DR Ensembl; ENSMUST00000019506; ENSMUSP00000019506; ENSMUSG00000019362.
DR GeneID; 101966; -.
DR KEGG; mmu:101966; -.
DR UCSC; uc012ghh.1; mouse.
DR CTD; 101966; -.
DR MGI; MGI:1289231; D8Ertd738e.
DR VEuPathDB; HostDB:ENSMUSG00000019362; -.
DR eggNOG; ENOG502S8BT; Eukaryota.
DR GeneTree; ENSGT00390000011740; -.
DR HOGENOM; CLU_182392_0_0_1; -.
DR InParanoid; Q8R1F0; -.
DR OMA; IEHEVTQ; -.
DR OrthoDB; 1629358at2759; -.
DR PhylomeDB; Q8R1F0; -.
DR TreeFam; TF333384; -.
DR BioGRID-ORCS; 101966; 16 hits in 75 CRISPR screens.
DR ChiTaRS; D8Ertd738e; mouse.
DR PRO; PR:Q8R1F0; -.
DR Proteomes; UP000000589; Chromosome 8.
DR RNAct; Q8R1F0; protein.
DR Bgee; ENSMUSG00000019362; Expressed in granulocyte and 250 other tissues.
DR Genevisible; Q8R1F0; MM.
DR InterPro; IPR019034; UPF0390.
DR PANTHER; PTHR16967; PTHR16967; 1.
DR Pfam; PF09495; DUF2462; 1.
PE 3: Inferred from homology;
KW Reference proteome.
FT CHAIN 1..94
FT /note="Leydig cell tumor 10 kDa protein homolog"
FT /id="PRO_0000255271"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 94 AA; 10197 MW; B88B86D19D7E4625 CRC64;
MAQGQRKFQA QKPKSKAAAA ERSRGPRKGG RVIAPKKARV VQQQKLKKSL EVGIRKKIEH
DVVMKASSSL PKRLALLKGA SKKSEATIPG KTPS