ID   ARCC1_STAA8             Reviewed;         310 AA.
AC   Q2FZA9;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Carbamate kinase 1;
DE            EC=2.7.2.2;
GN   Name=arcC1; OrderedLocusNames=SAOUHSC_01129;
OS   Staphylococcus aureus (strain NCTC 8325 / PS 47).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=93061;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC 8325 / PS 47;
RA   Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W., Iandolo J.J.;
RT   "The Staphylococcus aureus NCTC 8325 genome.";
RL   (In) Fischetti V., Novick R., Ferretti J., Portnoy D., Rood J. (eds.);
RL   Gram positive pathogens, 2nd edition, pp.381-412, ASM Press, Washington
RL   D.C. (2006).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + hydrogencarbonate + NH4(+) = ADP + carbamoyl phosphate +
CC         H(+) + H2O; Xref=Rhea:RHEA:10152, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:17544, ChEBI:CHEBI:28938,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:58228, ChEBI:CHEBI:456216; EC=2.7.2.2;
CC   -!- PATHWAY: Metabolic intermediate metabolism; carbamoyl phosphate
CC       degradation; CO(2) and NH(3) from carbamoyl phosphate: step 1/1.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the carbamate kinase family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000253; ABD30240.1; -; Genomic_DNA.
DR   RefSeq; WP_001074342.1; NZ_LS483365.1.
DR   RefSeq; YP_499672.1; NC_007795.1.
DR   AlphaFoldDB; Q2FZA9; -.
DR   SMR; Q2FZA9; -.
DR   STRING; 1280.SAXN108_1166; -.
DR   EnsemblBacteria; ABD30240; ABD30240; SAOUHSC_01129.
DR   GeneID; 3920729; -.
DR   KEGG; sao:SAOUHSC_01129; -.
DR   PATRIC; fig|93061.5.peg.1036; -.
DR   eggNOG; COG0549; Bacteria.
DR   HOGENOM; CLU_076278_0_0_9; -.
DR   OMA; DWCGAQT; -.
DR   UniPathway; UPA00996; UER00366.
DR   PRO; PR:Q2FZA9; -.
DR   Proteomes; UP000008816; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008804; F:carbamate kinase activity; IBA:GO_Central.
DR   GO; GO:0019546; P:arginine deiminase pathway; IBA:GO_Central.
DR   GO; GO:0035975; P:carbamoyl phosphate catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd04235; AAK_CK; 1.
DR   Gene3D; 3.40.1160.10; -; 1.
DR   InterPro; IPR036393; AceGlu_kinase-like_sf.
DR   InterPro; IPR001048; Asp/Glu/Uridylate_kinase.
DR   InterPro; IPR003964; Carb_kinase.
DR   PANTHER; PTHR30409; PTHR30409; 1.
DR   Pfam; PF00696; AA_kinase; 1.
DR   PIRSF; PIRSF000723; Carbamate_kin; 1.
DR   SUPFAM; SSF53633; SSF53633; 1.
DR   TIGRFAMs; TIGR00746; arcC; 1.
PE   3: Inferred from homology;
KW   Arginine metabolism; ATP-binding; Cytoplasm; Kinase; Nucleotide-binding;
KW   Reference proteome; Transferase.
FT   CHAIN           1..310
FT                   /note="Carbamate kinase 1"
FT                   /id="PRO_0000269240"
SQ   SEQUENCE   310 AA;  33596 MW;  04399CC277EB0BC7 CRC64;
     MAKIVVALGG NALGKSPQEQ LELVKNTAKS LVGLITKGHE IVISHGNGPQ VGSINLGLNY
     AAEHNQGPAF PFAECGAMSQ AYIGYQLQES LQNELHSIGM DKQVVTLVTQ VEVDENDPAF
     NNPSKPIGLF YNKEEAEQIQ KEKGFIFVED AGRGYRRVVP SPQPISIIEL ESIKTLIKND
     TLVIAAGGGG IPVIREQHDG FKGIDAVIDK DKTSALLGAN IQCDQLIILT AIDYVYINFN
     TENQQPLKTT NVDELKRYID ENQFAKGSML PKIEAAISFI ENNPKGSVLI TSLNELDAAL
     EGKVGTVIKK