ID   ARCC1_STAAM             Reviewed;         310 AA.
AC   Q99UU0;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Carbamate kinase 1;
DE            EC=2.7.2.2;
GN   Name=arcC1; OrderedLocusNames=SAV1170;
OS   Staphylococcus aureus (strain Mu50 / ATCC 700699).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=158878;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Mu50 / ATCC 700699;
RX   PubMed=11418146; DOI=10.1016/s0140-6736(00)04403-2;
RA   Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L.,
RA   Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M.,
RA   Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y.,
RA   Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H.,
RA   Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K.,
RA   Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H.,
RA   Hiramatsu K.;
RT   "Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
RL   Lancet 357:1225-1240(2001).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + hydrogencarbonate + NH4(+) = ADP + carbamoyl phosphate +
CC         H(+) + H2O; Xref=Rhea:RHEA:10152, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:17544, ChEBI:CHEBI:28938,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:58228, ChEBI:CHEBI:456216; EC=2.7.2.2;
CC   -!- PATHWAY: Metabolic intermediate metabolism; carbamoyl phosphate
CC       degradation; CO(2) and NH(3) from carbamoyl phosphate: step 1/1.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the carbamate kinase family. {ECO:0000305}.
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DR   EMBL; BA000017; BAB57332.1; -; Genomic_DNA.
DR   RefSeq; WP_001074342.1; NC_002758.2.
DR   AlphaFoldDB; Q99UU0; -.
DR   SMR; Q99UU0; -.
DR   PaxDb; Q99UU0; -.
DR   EnsemblBacteria; BAB57332; BAB57332; SAV1170.
DR   KEGG; sav:SAV1170; -.
DR   HOGENOM; CLU_076278_0_0_9; -.
DR   OMA; DWCGAQT; -.
DR   PhylomeDB; Q99UU0; -.
DR   BioCyc; SAUR158878:SAV_RS06310-MON; -.
DR   UniPathway; UPA00996; UER00366.
DR   Proteomes; UP000002481; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008804; F:carbamate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006525; P:arginine metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0035975; P:carbamoyl phosphate catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd04235; AAK_CK; 1.
DR   Gene3D; 3.40.1160.10; -; 1.
DR   InterPro; IPR036393; AceGlu_kinase-like_sf.
DR   InterPro; IPR001048; Asp/Glu/Uridylate_kinase.
DR   InterPro; IPR003964; Carb_kinase.
DR   PANTHER; PTHR30409; PTHR30409; 1.
DR   Pfam; PF00696; AA_kinase; 1.
DR   PIRSF; PIRSF000723; Carbamate_kin; 1.
DR   SUPFAM; SSF53633; SSF53633; 1.
DR   TIGRFAMs; TIGR00746; arcC; 1.
PE   3: Inferred from homology;
KW   Arginine metabolism; ATP-binding; Cytoplasm; Kinase; Nucleotide-binding;
KW   Transferase.
FT   CHAIN           1..310
FT                   /note="Carbamate kinase 1"
FT                   /id="PRO_0000269237"
SQ   SEQUENCE   310 AA;  33596 MW;  04399CC277EB0BC7 CRC64;
     MAKIVVALGG NALGKSPQEQ LELVKNTAKS LVGLITKGHE IVISHGNGPQ VGSINLGLNY
     AAEHNQGPAF PFAECGAMSQ AYIGYQLQES LQNELHSIGM DKQVVTLVTQ VEVDENDPAF
     NNPSKPIGLF YNKEEAEQIQ KEKGFIFVED AGRGYRRVVP SPQPISIIEL ESIKTLIKND
     TLVIAAGGGG IPVIREQHDG FKGIDAVIDK DKTSALLGAN IQCDQLIILT AIDYVYINFN
     TENQQPLKTT NVDELKRYID ENQFAKGSML PKIEAAISFI ENNPKGSVLI TSLNELDAAL
     EGKVGTVIKK