ID   L83L_ASFB7              Reviewed;          83 AA.
AC   Q65132;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   23-FEB-2022, entry version 58.
DE   RecName: Full=Protein L83L;
GN   OrderedLocusNames=BA71V-006; ORFNames=L83L;
OS   African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V)
OS   (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=10498;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11831707; DOI=10.1006/viro.1995.1149;
RA   Yanez R.J., Rodriguez J.M., Nogal M.L., Yuste L., Enriquez C.,
RA   Rodriguez J.F., Vinuela E.;
RT   "Analysis of the complete nucleotide sequence of African swine fever
RT   virus.";
RL   Virology 208:249-278(1995).
RN   [2]
RP   SUBCELLULAR LOCATION, FUNCTION, INTERACTION WITH HOST IL1B, AND INDUCTION.
RC   STRAIN=Georgia;
RX   PubMed=29605728; DOI=10.1016/j.virusres.2018.03.017;
RA   Borca M.V., O'Donnell V., Holinka L.G., Ramirez-Medina E., Clark B.A.,
RA   Vuono E.A., Berggren K., Alfano M., Carey L.B., Richt J.A., Risatti G.R.,
RA   Gladue D.P.;
RT   "The L83L ORF of African swine fever virus strain Georgia encodes for a
RT   non-essential gene that interacts with the host protein IL-1beta.";
RL   Virus Res. 249:116-123(2018).
RN   [3]
RP   INDUCTION.
RX   PubMed=32075923; DOI=10.1128/jvi.00119-20;
RA   Cackett G., Matelska D., Sykora M., Portugal R., Malecki M., Baehler J.,
RA   Dixon L., Werner F.;
RT   "The African Swine Fever Virus Transcriptome.";
RL   J. Virol. 94:0-0(2020).
CC   -!- FUNCTION: May subvert the host innate immune response by interacting
CC       with host IL1B and interfering with its function.
CC       {ECO:0000269|PubMed:29605728}.
CC   -!- SUBUNIT: Interacts with host IL1B. {ECO:0000269|PubMed:29605728}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000269|PubMed:29605728}.
CC   -!- INDUCTION: Expressed in the early phase of the viral replicative cycle.
CC       {ECO:0000269|PubMed:29605728, ECO:0000269|PubMed:32075923}.
CC   -!- SIMILARITY: Belongs to the asfivirus L83L family. {ECO:0000305}.
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DR   EMBL; U18466; AAA65241.1; -; Genomic_DNA.
DR   RefSeq; NP_042705.1; NC_001659.2.
DR   GeneID; 22220395; -.
DR   KEGG; vg:22220395; -.
DR   Proteomes; UP000000624; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
PE   1: Evidence at protein level;
KW   Early protein; Host cytoplasm; Host-virus interaction; Reference proteome.
FT   CHAIN           1..83
FT                   /note="Protein L83L"
FT                   /id="PRO_0000373734"
SQ   SEQUENCE   83 AA;  9583 MW;  C6538626BFB9CBFF CRC64;
     MIMDTSLKNN DGALEADNKN YQDYKAEPDK TSDVLDVTKY NSVVDCCHKN YSTFTSEWYI
     NERKYNDVPE GPKKAVVHRC TIL