LA1_MESMA
ID LA1_MESMA Reviewed; 123 AA.
AC D2CFI7; Q95P92;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 09-FEB-2010, sequence version 1.
DT 25-MAY-2022, entry version 18.
DE RecName: Full=Venom peptide MmKTx1;
DE AltName: Full=BmTXLP1;
DE AltName: Full=BmTXLP4;
DE Flags: Precursor;
OS Mesobuthus martensii (Manchurian scorpion) (Buthus martensii).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida;
OC Scorpiones; Buthida; Buthoidea; Buthidae; Mesobuthus.
OX NCBI_TaxID=34649;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Venom gland;
RX PubMed=23099316; DOI=10.1016/j.peptides.2012.10.004;
RA Zeng X.C., Nie Y., Luo X., Wu S., Shi W., Zhang L., Liu Y., Cao H.,
RA Yang Y., Zhou J.;
RT "Molecular and bioinformatical characterization of a novel superfamily of
RT cysteine-rich peptides from arthropods.";
RL Peptides 41:45-58(2013).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 48-123.
RC TISSUE=Venom gland;
RA Zhu S., Li W.;
RL Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC -!- PTM: Contains 4 disulfide bonds. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the scorpion La1-like peptide family.
CC {ECO:0000305}.
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DR EMBL; DQ352540; ABC86160.1; -; mRNA.
DR EMBL; EF063687; ABN04116.1; -; mRNA.
DR EMBL; JQ821371; AFR60583.1; -; mRNA.
DR EMBL; AF155366; AAK61816.1; -; mRNA.
DR AlphaFoldDB; D2CFI7; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR InterPro; IPR029277; SVWC_dom.
DR Pfam; PF15430; SVWC; 1.
DR SMART; SM01318; SVWC; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond; Secreted; Signal; Toxin.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..123
FT /note="Venom peptide MmKTx1"
FT /id="PRO_0000428817"
SQ SEQUENCE 123 AA; 13923 MW; F03887018B2D3158 CRC64;
MSIKISAIAL FMLSFTVFVN GIPFFLTKGR IDTCKTLTGE TIKIGESWHD PNSCSVYYCE
VNSLGAMLIG KTCATVFYPS NCREEPGTGL YPDCCNKVVC GEEEMVVYPY EERSLRRYYF
SKF