ID   LA1_OPICY               Reviewed;          98 AA.
AC   C5J895;
DT   19-OCT-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 18.
DE   RecName: Full=Venom toxin OcyC11;
DE            Short=VTX;
DE   Flags: Precursor;
OS   Opisthacanthus cayaporum (South American scorpion).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida;
OC   Scorpiones; Iurida; Scorpionoidea; Hemiscorpiidae; Opisthacanthus.
OX   NCBI_TaxID=573324;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Venom gland;
RX   PubMed=19379768; DOI=10.1016/j.toxicon.2009.04.010;
RA   Silva E.C., Camargos T.S., Maranhao A.Q., Silva-Pereira I., Silva L.P.,
RA   Possani L.D., Schwartz E.F.;
RT   "Cloning and characterization of cDNA sequences encoding for new venom
RT   peptides of the Brazilian scorpion Opisthacanthus cayaporum.";
RL   Toxicon 54:252-261(2009).
RN   [2]
RP   MASS SPECTROMETRY.
RC   TISSUE=Venom;
RX   PubMed=18502464; DOI=10.1016/j.toxicon.2008.03.029;
RA   Schwartz E.F., Camargos T.S., Zamudio F.Z., Silva L.P., Bloch C. Jr.,
RA   Caixeta F., Schwartz C.A., Possani L.D.;
RT   "Mass spectrometry analysis, amino acid sequence and biological activity of
RT   venom components from the Brazilian scorpion Opisthacanthus cayaporum.";
RL   Toxicon 51:1499-1508(2008).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC   -!- PTM: Contains 4 disulfide bonds.
CC   -!- MASS SPECTROMETRY: Mass=8558.0; Method=Electrospray;
CC       Evidence={ECO:0000269|PubMed:18502464};
CC   -!- SIMILARITY: Belongs to the scorpion La1-like peptide family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FM998753; CAX51399.1; -; mRNA.
DR   AlphaFoldDB; C5J895; -.
DR   SMR; C5J895; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   InterPro; IPR029277; SVWC_dom.
DR   Pfam; PF15430; SVWC; 1.
DR   SMART; SM01318; SVWC; 1.
PE   1: Evidence at protein level;
KW   Disulfide bond; Secreted; Signal; Toxin.
FT   SIGNAL          1..20
FT   CHAIN           21..98
FT                   /note="Venom toxin OcyC11"
FT                   /id="PRO_0000413159"
SQ   SEQUENCE   98 AA;  10894 MW;  C60B5CAF36DB9068 CRC64;
     MKIACTLVLF VMLRCYVNAR NIPGTCRTHT GIILLSGEEW KDPNHCSTYR CSIFDGEAEL
     EGVTCAAYHV PPHCRLVSAA NELYPQCCPT VICSDKSR