ID   ARCC2_STAA8             Reviewed;         313 AA.
AC   Q7X2S2; Q2FUY0;
DT   28-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Carbamate kinase 2;
DE            EC=2.7.2.2;
GN   Name=arcC2; Synonyms=arcC; OrderedLocusNames=SAOUHSC_02965;
OS   Staphylococcus aureus (strain NCTC 8325 / PS 47).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=93061;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Makhlin J., Aharonowitz Y., Cohen G., Borovok I.;
RT   "Organization, transcriptional and functional analysis of the arcABDCR
RT   operon in Staphylococcus aureus.";
RL   Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC 8325 / PS 47;
RA   Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W., Iandolo J.J.;
RT   "The Staphylococcus aureus NCTC 8325 genome.";
RL   (In) Fischetti V., Novick R., Ferretti J., Portnoy D., Rood J. (eds.);
RL   Gram positive pathogens, 2nd edition, pp.381-412, ASM Press, Washington
RL   D.C. (2006).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + hydrogencarbonate + NH4(+) = ADP + carbamoyl phosphate +
CC         H(+) + H2O; Xref=Rhea:RHEA:10152, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:17544, ChEBI:CHEBI:28938,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:58228, ChEBI:CHEBI:456216; EC=2.7.2.2;
CC   -!- PATHWAY: Metabolic intermediate metabolism; carbamoyl phosphate
CC       degradation; CO(2) and NH(3) from carbamoyl phosphate: step 1/1.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the carbamate kinase family. {ECO:0000305}.
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DR   EMBL; AJ566750; CAD98184.1; -; Genomic_DNA.
DR   EMBL; CP000253; ABD31955.1; -; Genomic_DNA.
DR   RefSeq; WP_000660034.1; NZ_LS483365.1.
DR   RefSeq; YP_501416.1; NC_007795.1.
DR   AlphaFoldDB; Q7X2S2; -.
DR   SMR; Q7X2S2; -.
DR   STRING; 1280.SAXN108_2903; -.
DR   EnsemblBacteria; ABD31955; ABD31955; SAOUHSC_02965.
DR   GeneID; 3921667; -.
DR   KEGG; sao:SAOUHSC_02965; -.
DR   PATRIC; fig|93061.5.peg.2675; -.
DR   eggNOG; COG0549; Bacteria.
DR   HOGENOM; CLU_076278_0_0_9; -.
DR   OMA; QPMDVAG; -.
DR   UniPathway; UPA00996; UER00366.
DR   PRO; PR:Q7X2S2; -.
DR   Proteomes; UP000008816; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008804; F:carbamate kinase activity; IBA:GO_Central.
DR   GO; GO:0019546; P:arginine deiminase pathway; IBA:GO_Central.
DR   GO; GO:0035975; P:carbamoyl phosphate catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd04235; AAK_CK; 1.
DR   Gene3D; 3.40.1160.10; -; 1.
DR   InterPro; IPR036393; AceGlu_kinase-like_sf.
DR   InterPro; IPR001048; Asp/Glu/Uridylate_kinase.
DR   InterPro; IPR003964; Carb_kinase.
DR   PANTHER; PTHR30409; PTHR30409; 1.
DR   Pfam; PF00696; AA_kinase; 1.
DR   PIRSF; PIRSF000723; Carbamate_kin; 1.
DR   SUPFAM; SSF53633; SSF53633; 1.
DR   TIGRFAMs; TIGR00746; arcC; 1.
PE   3: Inferred from homology;
KW   Arginine metabolism; ATP-binding; Cytoplasm; Kinase; Nucleotide-binding;
KW   Reference proteome; Transferase.
FT   CHAIN           1..313
FT                   /note="Carbamate kinase 2"
FT                   /id="PRO_0000185138"
SQ   SEQUENCE   313 AA;  34329 MW;  4BE10AD392BF87C8 CRC64;
     MKEKIVIALG GNAIQTTEAT AEAQQTAIRC AMQNLKPLFD SPARIVISHG NGPQIGSLLI
     QQAKSNSDTT PAMPLDTCGA MSQGMIGYWL ETEINRILTE MNSDRTVGTI VTRVEVDKDD
     PRFDNPTKPI GPFYTKEEVE ELQKEQPDSV FKEDAGRGYR KVVASPLPQS ILEHQLIRTL
     ADGKNIVIAC GGGGIPVIKK ENTYEGVEAV IDKDFASEKL ATLIEADTLM ILTNVENVFI
     NFNEPNQQQI DDIDVATLKK YAAQGKFVEG SMLPKIEAAI RFVESGENKK VIITNLEQAY
     EALIGNKGTH IHM