ID   ARCC2_STAAB             Reviewed;         313 AA.
AC   Q2YWH4;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   12-DEC-2006, sequence version 2.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Carbamate kinase 2;
DE            EC=2.7.2.2;
GN   Name=arcC2; OrderedLocusNames=SAB2507c;
OS   Staphylococcus aureus (strain bovine RF122 / ET3-1).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=273036;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=bovine RF122 / ET3-1;
RX   PubMed=17971880; DOI=10.1371/journal.pone.0001120;
RA   Herron-Olson L., Fitzgerald J.R., Musser J.M., Kapur V.;
RT   "Molecular correlates of host specialization in Staphylococcus aureus.";
RL   PLoS ONE 2:E1120-E1120(2007).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + hydrogencarbonate + NH4(+) = ADP + carbamoyl phosphate +
CC         H(+) + H2O; Xref=Rhea:RHEA:10152, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:17544, ChEBI:CHEBI:28938,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:58228, ChEBI:CHEBI:456216; EC=2.7.2.2;
CC   -!- PATHWAY: Metabolic intermediate metabolism; carbamoyl phosphate
CC       degradation; CO(2) and NH(3) from carbamoyl phosphate: step 1/1.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the carbamate kinase family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAI82195.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AJ938182; CAI82195.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_000660033.1; NC_007622.1.
DR   AlphaFoldDB; Q2YWH4; -.
DR   SMR; Q2YWH4; -.
DR   KEGG; sab:SAB2507c; -.
DR   HOGENOM; CLU_076278_0_0_9; -.
DR   UniPathway; UPA00996; UER00366.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008804; F:carbamate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006525; P:arginine metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0035975; P:carbamoyl phosphate catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd04235; AAK_CK; 1.
DR   Gene3D; 3.40.1160.10; -; 1.
DR   InterPro; IPR036393; AceGlu_kinase-like_sf.
DR   InterPro; IPR001048; Asp/Glu/Uridylate_kinase.
DR   InterPro; IPR003964; Carb_kinase.
DR   PANTHER; PTHR30409; PTHR30409; 1.
DR   Pfam; PF00696; AA_kinase; 1.
DR   PIRSF; PIRSF000723; Carbamate_kin; 1.
DR   SUPFAM; SSF53633; SSF53633; 1.
DR   TIGRFAMs; TIGR00746; arcC; 1.
PE   3: Inferred from homology;
KW   Arginine metabolism; ATP-binding; Cytoplasm; Kinase; Nucleotide-binding;
KW   Transferase.
FT   CHAIN           1..313
FT                   /note="Carbamate kinase 2"
FT                   /id="PRO_0000269233"
SQ   SEQUENCE   313 AA;  34408 MW;  4D2BF90E0C66C967 CRC64;
     MKEKIVIALG GNAIQTKEAT AEAQQTAIRR AMQNLKPLFD SPARIVISHG NGPQIGSLLI
     QQAKSNSDTT PAMPLDTCGA MSQGMIGYWL ETEINRILTE MNSDRTVGTI VTRVEVDKND
     PRFDNPTKPI GPFYTKEEVE ELQKEQPDSV FKEDAGRGYR KVVASPLPQS ILEHQLIRTL
     ADGKNIVIAC GGGGIPVIKK ENTYEGVEAV IDKDFASEKL ATLIEADTLM ILTNVENVFI
     NFNEPNQQQI DDIDVATLKK YVAQGKFAEG SMLPKIEAAI RFVESGENKK VIITNLEQAY
     EALIGNKGTH IHM