ID   LAC1_RAT                Reviewed;         104 AA.
AC   P20766;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=Ig lambda-1 chain C region;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3114047; DOI=10.1016/0378-1119(87)90250-2;
RA   Steen M.L., Hellman L., Pettersson U.;
RT   "The immunoglobulin lambda locus in rat consists of two C lambda genes and
RT   a single V lambda gene.";
RL   Gene 55:75-84(1987).
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA41419.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; M22520; AAA41419.1; ALT_INIT; Genomic_DNA.
DR   PIR; A27390; A27390.
DR   AlphaFoldDB; P20766; -.
DR   SMR; P20766; -.
DR   PaxDb; P20766; -.
DR   ABCD; P20766; 1 sequenced antibody.
DR   Ensembl; ENSRNOT00000057971; ENSRNOP00000054780; ENSRNOG00000050000.
DR   RGD; 1564318; RGD1564318.
DR   eggNOG; ENOG502TFGC; Eukaryota.
DR   GeneTree; ENSGT00940000153307; -.
DR   HOGENOM; CLU_077975_6_3_1; -.
DR   InParanoid; P20766; -.
DR   PRO; PR:P20766; -.
DR   Proteomes; UP000002494; Chromosome 11.
DR   Genevisible; P20766; RN.
DR   GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR   GO; GO:0042571; C:immunoglobulin complex, circulating; IBA:GO_Central.
DR   GO; GO:0003823; F:antigen binding; IBA:GO_Central.
DR   GO; GO:0034987; F:immunoglobulin receptor binding; IBA:GO_Central.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; IBA:GO_Central.
DR   GO; GO:0006958; P:complement activation, classical pathway; IBA:GO_Central.
DR   GO; GO:0042742; P:defense response to bacterium; IBA:GO_Central.
DR   GO; GO:0045087; P:innate immune response; IBA:GO_Central.
DR   GO; GO:0006911; P:phagocytosis, engulfment; IBA:GO_Central.
DR   GO; GO:0006910; P:phagocytosis, recognition; IBA:GO_Central.
DR   GO; GO:0050871; P:positive regulation of B cell activation; IBA:GO_Central.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003006; Ig/MHC_CS.
DR   InterPro; IPR003597; Ig_C1-set.
DR   Pfam; PF07654; C1-set; 1.
DR   SMART; SM00407; IGc1; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
DR   PROSITE; PS00290; IG_MHC; 1.
PE   4: Predicted;
KW   Disulfide bond; Immunoglobulin domain; Reference proteome.
FT   CHAIN           <1..104
FT                   /note="Ig lambda-1 chain C region"
FT                   /id="PRO_0000153615"
FT   DOMAIN          6..99
FT                   /note="Ig-like"
FT   DISULFID        27..85
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT   DISULFID        103
FT                   /note="Interchain (with heavy chain)"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT   NON_TER         1
SQ   SEQUENCE   104 AA;  11565 MW;  CBF71811F4BC878A CRC64;
     QPKATPSVTL FPPSSEELKT DKATLVCMVT DFYPGVMTVV WKADGTPITQ GVETTQPFKQ
     NNKYMATSYL LLTAKAWETH SNYSCQVTHE ENTVEKSLSR AECS