ID   ARCC3_STAA3             Reviewed;         309 AA.
AC   Q2FKJ8;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Carbamate kinase 3;
DE            EC=2.7.2.2;
GN   Name=arcC3; OrderedLocusNames=SAUSA300_0061;
OS   Staphylococcus aureus (strain USA300).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=367830;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=USA300;
RX   PubMed=16517273; DOI=10.1016/s0140-6736(06)68231-7;
RA   Diep B.A., Gill S.R., Chang R.F., Phan T.H., Chen J.H., Davidson M.G.,
RA   Lin F., Lin J., Carleton H.A., Mongodin E.F., Sensabaugh G.F.,
RA   Perdreau-Remington F.;
RT   "Complete genome sequence of USA300, an epidemic clone of community-
RT   acquired meticillin-resistant Staphylococcus aureus.";
RL   Lancet 367:731-739(2006).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + hydrogencarbonate + NH4(+) = ADP + carbamoyl phosphate +
CC         H(+) + H2O; Xref=Rhea:RHEA:10152, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:17544, ChEBI:CHEBI:28938,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:58228, ChEBI:CHEBI:456216; EC=2.7.2.2;
CC   -!- PATHWAY: Metabolic intermediate metabolism; carbamoyl phosphate
CC       degradation; CO(2) and NH(3) from carbamoyl phosphate: step 1/1.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the carbamate kinase family. {ECO:0000305}.
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DR   EMBL; CP000255; ABD20922.1; -; Genomic_DNA.
DR   RefSeq; WP_000036757.1; NZ_CP027476.1.
DR   AlphaFoldDB; Q2FKJ8; -.
DR   SMR; Q2FKJ8; -.
DR   EnsemblBacteria; ABD20922; ABD20922; SAUSA300_0061.
DR   KEGG; saa:SAUSA300_0061; -.
DR   HOGENOM; CLU_076278_0_0_9; -.
DR   OMA; ETTPYPM; -.
DR   UniPathway; UPA00996; UER00366.
DR   Proteomes; UP000001939; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008804; F:carbamate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006525; P:arginine metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0035975; P:carbamoyl phosphate catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd04235; AAK_CK; 1.
DR   Gene3D; 3.40.1160.10; -; 1.
DR   InterPro; IPR036393; AceGlu_kinase-like_sf.
DR   InterPro; IPR001048; Asp/Glu/Uridylate_kinase.
DR   InterPro; IPR003964; Carb_kinase.
DR   PANTHER; PTHR30409; PTHR30409; 1.
DR   Pfam; PF00696; AA_kinase; 1.
DR   PIRSF; PIRSF000723; Carbamate_kin; 1.
DR   SUPFAM; SSF53633; SSF53633; 1.
DR   TIGRFAMs; TIGR00746; arcC; 1.
PE   3: Inferred from homology;
KW   Arginine metabolism; ATP-binding; Cytoplasm; Kinase; Nucleotide-binding;
KW   Transferase.
FT   CHAIN           1..309
FT                   /note="Carbamate kinase 3"
FT                   /id="PRO_0000269243"
SQ   SEQUENCE   309 AA;  33157 MW;  2A5543CF1E26F76E CRC64;
     MSKIVVALGG NALGQSPKEQ LDLLKSTSKS LVSLIDKGYE IVISHGNGPQ VGSINLGLNY
     AAEHKQGPPF PFPECGAMSQ AYIGYQMQES LQNELHSMGI DKQVVTLVTQ VQVASDDSAF
     NNPTKPIGLF YTKEQADKFT KEKGYTFVED SGRGYRRVVP SPQPISIVEL DSIETLITHG
     TLVIAAGGGG IPVIKENEVY TGVDAVIDKD KTSALLAAHL QSDQLIILTA VDHVYINYGK
     ENQRGLDEVS VDEMKKHISD GQFAKGSMLP KVEAALQFLE KNTKGSVLIT SLAGLGDALD
     GKIGTLIKN