ID   ARCC_LENHI              Reviewed;         318 AA.
AC   Q8G997;
DT   23-APR-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Carbamate kinase;
DE            EC=2.7.2.2;
GN   Name=arcC;
OS   Lentilactobacillus hilgardii (Lactobacillus hilgardii).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lentilactobacillus.
OX   NCBI_TaxID=1588;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=X(1)B;
RX   PubMed=12490324; DOI=10.1016/s0378-1119(02)01083-1;
RA   Arena M.E., Manca de Nadra M.C., Munoz R.;
RT   "The arginine deiminase pathway in the wine lactic acid bacterium
RT   Lactobacillus hilgardii X1B: structural and functional study of the arcABC
RT   genes.";
RL   Gene 301:61-66(2002).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + hydrogencarbonate + NH4(+) = ADP + carbamoyl phosphate +
CC         H(+) + H2O; Xref=Rhea:RHEA:10152, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:17544, ChEBI:CHEBI:28938,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:58228, ChEBI:CHEBI:456216; EC=2.7.2.2;
CC   -!- PATHWAY: Metabolic intermediate metabolism; carbamoyl phosphate
CC       degradation; CO(2) and NH(3) from carbamoyl phosphate: step 1/1.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the carbamate kinase family. {ECO:0000305}.
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DR   EMBL; AJ421514; CAD13393.1; -; Genomic_DNA.
DR   RefSeq; WP_003634647.1; NZ_PUFR01000061.1.
DR   AlphaFoldDB; Q8G997; -.
DR   SMR; Q8G997; -.
DR   UniPathway; UPA00996; UER00366.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008804; F:carbamate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006525; P:arginine metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0035975; P:carbamoyl phosphate catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd04235; AAK_CK; 1.
DR   Gene3D; 3.40.1160.10; -; 1.
DR   InterPro; IPR036393; AceGlu_kinase-like_sf.
DR   InterPro; IPR001048; Asp/Glu/Uridylate_kinase.
DR   InterPro; IPR003964; Carb_kinase.
DR   PANTHER; PTHR30409; PTHR30409; 1.
DR   Pfam; PF00696; AA_kinase; 1.
DR   PIRSF; PIRSF000723; Carbamate_kin; 1.
DR   SUPFAM; SSF53633; SSF53633; 1.
DR   TIGRFAMs; TIGR00746; arcC; 1.
PE   3: Inferred from homology;
KW   Arginine metabolism; ATP-binding; Cytoplasm; Kinase; Nucleotide-binding;
KW   Transferase.
FT   CHAIN           1..318
FT                   /note="Carbamate kinase"
FT                   /id="PRO_0000185126"
SQ   SEQUENCE   318 AA;  33602 MW;  90D0A16A3C25B796 CRC64;
     MGRKIVVALG GNAILSKDAS AAAQQQALMD TAKHLVKFIE NGDQLIISHG NGPQVGNLLL
     QQSAGSTEEN PAMPLDTAVA MTQGSIGYWM QNAMNQVLKE KGLNKTVATV VTQVEVSADD
     PAFTNPTKPI GPFMSKDEAD LAKKENPDFT FVEDAGRGYR RVVPSPKPIG VVETDAVNTL
     VDAGIVPISV GGGGIPVVAD GNQLLGREAV IDKDFASEKL AELVGADALI ILTAVPNIYV
     NFNKPNQKKL EHVSVNDLET YISEKQFAPG SMLPKVQAAI DFVKATGNEA VVTALDNIEG
     FVNEGSGTVI TKKVRQQA