ID   LACB_TRIVU              Reviewed;         174 AA.
AC   Q29146;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Beta-lactoglobulin;
DE            Short=Beta-LG;
DE   Flags: Precursor;
GN   Name=LGB;
OS   Trichosurus vulpecula (Brush-tailed possum).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Metatheria; Diprotodontia; Phalangeridae; Trichosurus.
OX   NCBI_TaxID=9337;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Mammary gland;
RX   PubMed=9493361; DOI=10.1007/pl00006313;
RA   Piotte C.P., Hunter A.K., Marshall C.J., Grigor M.R.;
RT   "Phylogenetic analysis of three lipocalin-like proteins present in the milk
RT   of Trichosurus vulpecula (Phalangeridae, Marsupialia).";
RL   J. Mol. Evol. 46:361-369(1998).
CC   -!- FUNCTION: Lactoglobulin is the primary component of whey, it binds
CC       retinol and is probably involved in the transport of that molecule.
CC   -!- SUBUNIT: Monomer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the calycin superfamily. Lipocalin family.
CC       {ECO:0000305}.
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DR   EMBL; U34289; AAA93180.1; -; mRNA.
DR   AlphaFoldDB; Q29146; -.
DR   SMR; Q29146; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0019841; F:retinol binding; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.128.20; -; 1.
DR   InterPro; IPR012674; Calycin.
DR   InterPro; IPR002345; Lipocalin.
DR   InterPro; IPR000566; Lipocln_cytosolic_FA-bd_dom.
DR   PANTHER; PTHR11430; PTHR11430; 1.
DR   Pfam; PF00061; Lipocalin; 1.
DR   SUPFAM; SSF50814; SSF50814; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Milk protein; Retinol-binding; Secreted; Signal; Transport.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000250"
FT   CHAIN           19..174
FT                   /note="Beta-lactoglobulin"
FT                   /id="PRO_0000017911"
FT   DISULFID        79..172
FT                   /evidence="ECO:0000250"
FT   DISULFID        122..134
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   174 AA;  20306 MW;  3577B4E75BCC1417 CRC64;
     MKFLLLTVGL TSICAIQAIE NIHSKEELVV EKLIGPWYRV EEAKAMEFSI PLFDMNIKEV
     NRTPEGNLEL IVLEQTDSCV EKKFLLKKTE KPAEFEIYIP SESASYTLSV METDYDNYIL
     GCLENVNYRE KMACAHYERR IEENKGMEEF KKIVRTLTIP YTMIEAQTRE MCRV