ARCC_RHIET
ID ARCC_RHIET Reviewed; 310 AA.
AC O31019;
DT 01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 88.
DE RecName: Full=Carbamate kinase;
DE EC=2.7.2.2;
GN Name=arcC;
OS Rhizobium etli.
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX NCBI_TaxID=29449;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=9393705; DOI=10.1128/jb.179.23.7403-7409.1997;
RA D'Hooghe I., Vander Wauwe C., Michiels J., Tricot C., de Wilde P.,
RA Vanderleyden J., Stalon V.;
RT "The arginine deiminase pathway in Rhizobium etli: DNA sequence analysis
RT and functional study of the arcABC genes.";
RL J. Bacteriol. 179:7403-7409(1997).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + hydrogencarbonate + NH4(+) = ADP + carbamoyl phosphate +
CC H(+) + H2O; Xref=Rhea:RHEA:10152, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:17544, ChEBI:CHEBI:28938,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:58228, ChEBI:CHEBI:456216; EC=2.7.2.2;
CC -!- PATHWAY: Metabolic intermediate metabolism; carbamoyl phosphate
CC degradation; CO(2) and NH(3) from carbamoyl phosphate: step 1/1.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the carbamate kinase family. {ECO:0000305}.
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DR EMBL; AF025543; AAC46020.1; -; Genomic_DNA.
DR AlphaFoldDB; O31019; -.
DR SMR; O31019; -.
DR STRING; 491916.RHECIAT_CH0000126; -.
DR UniPathway; UPA00996; UER00366.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0008804; F:carbamate kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0006525; P:arginine metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0035975; P:carbamoyl phosphate catabolic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd04235; AAK_CK; 1.
DR Gene3D; 3.40.1160.10; -; 1.
DR InterPro; IPR036393; AceGlu_kinase-like_sf.
DR InterPro; IPR001048; Asp/Glu/Uridylate_kinase.
DR InterPro; IPR003964; Carb_kinase.
DR PANTHER; PTHR30409; PTHR30409; 1.
DR Pfam; PF00696; AA_kinase; 1.
DR PIRSF; PIRSF000723; Carbamate_kin; 1.
DR SUPFAM; SSF53633; SSF53633; 1.
DR TIGRFAMs; TIGR00746; arcC; 1.
PE 3: Inferred from homology;
KW Arginine metabolism; ATP-binding; Cytoplasm; Kinase; Nucleotide-binding;
KW Transferase.
FT CHAIN 1..310
FT /note="Carbamate kinase"
FT /id="PRO_0000185130"
SQ SEQUENCE 310 AA; 33504 MW; 50115ABC1D597224 CRC64;
MRVVIALGGN ALLRRGEAMT ADTQRRNARI AAQAIAPLAA DHEIVITHGN GPQVGLLALQ
GAAYKPEEAY PLDVLGAETE GMIGYMLEQE LGNLLPFEQP LATLLTMVEV DADDPGFQNP
TKFVGPVYDQ AEADRIRTEK GWVFKQDGEK WRRVVASPVP KRIFEIRPVR WLLEQRTIVI
CAGGGGIPTM YEKGANRKLS LEAVIDKDLC SGLLARELNA DLLIMATDAE TVCLDWGKPS
QKAIHRARPD DLTQFSFPAG SMGPKVDAAC HFARSGNRTA AIGSLADIAG LVRGERGTII
NGGFAALGWH