ID   ARCC_STAHJ              Reviewed;         309 AA.
AC   Q4L9V7;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   12-DEC-2006, sequence version 2.
DT   03-AUG-2022, entry version 122.
DE   RecName: Full=Carbamate kinase;
DE            EC=2.7.2.2;
GN   Name=arcC; OrderedLocusNames=SH0259;
OS   Staphylococcus haemolyticus (strain JCSC1435).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=279808;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCSC1435;
RX   PubMed=16237012; DOI=10.1128/jb.187.21.7292-7308.2005;
RA   Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y.,
RA   Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C.,
RA   Hiramatsu K.;
RT   "Whole-genome sequencing of Staphylococcus haemolyticus uncovers the
RT   extreme plasticity of its genome and the evolution of human-colonizing
RT   staphylococcal species.";
RL   J. Bacteriol. 187:7292-7308(2005).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + hydrogencarbonate + NH4(+) = ADP + carbamoyl phosphate +
CC         H(+) + H2O; Xref=Rhea:RHEA:10152, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:17544, ChEBI:CHEBI:28938,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:58228, ChEBI:CHEBI:456216; EC=2.7.2.2;
CC   -!- PATHWAY: Metabolic intermediate metabolism; carbamoyl phosphate
CC       degradation; CO(2) and NH(3) from carbamoyl phosphate: step 1/1.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the carbamate kinase family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAE03568.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AP006716; BAE03568.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_011274588.1; NC_007168.1.
DR   AlphaFoldDB; Q4L9V7; -.
DR   SMR; Q4L9V7; -.
DR   STRING; 279808.SH0259; -.
DR   EnsemblBacteria; BAE03568; BAE03568; SH0259.
DR   KEGG; sha:SH0259; -.
DR   eggNOG; COG0549; Bacteria.
DR   HOGENOM; CLU_076278_0_0_9; -.
DR   OrthoDB; 901370at2; -.
DR   UniPathway; UPA00996; UER00366.
DR   Proteomes; UP000000543; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008804; F:carbamate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006525; P:arginine metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0035975; P:carbamoyl phosphate catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd04235; AAK_CK; 1.
DR   Gene3D; 3.40.1160.10; -; 1.
DR   InterPro; IPR036393; AceGlu_kinase-like_sf.
DR   InterPro; IPR001048; Asp/Glu/Uridylate_kinase.
DR   InterPro; IPR003964; Carb_kinase.
DR   PANTHER; PTHR30409; PTHR30409; 1.
DR   Pfam; PF00696; AA_kinase; 1.
DR   PIRSF; PIRSF000723; Carbamate_kin; 1.
DR   SUPFAM; SSF53633; SSF53633; 1.
DR   TIGRFAMs; TIGR00746; arcC; 1.
PE   3: Inferred from homology;
KW   Arginine metabolism; ATP-binding; Cytoplasm; Kinase; Nucleotide-binding;
KW   Transferase.
FT   CHAIN           1..309
FT                   /note="Carbamate kinase"
FT                   /id="PRO_0000269245"
SQ   SEQUENCE   309 AA;  33127 MW;  B85DAAFC53D93149 CRC64;
     MSKIVVALGG NALGQSPEEQ LELVKGTAKS LVSLIQKGYE VVISHGNGPQ VGSINLGLNY
     AAENGQGPAF PFPECGAMSQ AYIGYQLQES LLNELHVLNI DKQVVTLVTQ VEVAGDDQAF
     NNPTKPIGLF YTKEQAEQTM EEKGYKFVED SGRGYRRVVP SPMPINIVEL DSIETLIKHG
     TLVIAAGGGG IPVVKEEGNY KGVDAVIDKD KTSALLAAHL KSDQLIILTA VDYVYINYGK
     DNQEALGEVT VDEMNQHIAD GQFAKGSMLP KVEAALQFIE KNPEGSVLIT SLEDLGDALD
     GKIGTLIKK