ID   ARCC_THEAC              Reviewed;         305 AA.
AC   Q9HII9;
DT   23-APR-2003, integrated into UniProtKB/Swiss-Prot.
DT   23-APR-2003, sequence version 2.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Carbamate kinase;
DE            EC=2.7.2.2;
GN   Name=arcC; OrderedLocusNames=Ta1350;
OS   Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC
OS   15155 / AMRC-C165).
OC   Archaea; Candidatus Thermoplasmatota; Thermoplasmata; Thermoplasmatales;
OC   Thermoplasmataceae; Thermoplasma.
OX   NCBI_TaxID=273075;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165;
RX   PubMed=11029001; DOI=10.1038/35035069;
RA   Ruepp A., Graml W., Santos-Martinez M.-L., Koretke K.K., Volker C.,
RA   Mewes H.-W., Frishman D., Stocker S., Lupas A.N., Baumeister W.;
RT   "The genome sequence of the thermoacidophilic scavenger Thermoplasma
RT   acidophilum.";
RL   Nature 407:508-513(2000).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + hydrogencarbonate + NH4(+) = ADP + carbamoyl phosphate +
CC         H(+) + H2O; Xref=Rhea:RHEA:10152, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:17544, ChEBI:CHEBI:28938,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:58228, ChEBI:CHEBI:456216; EC=2.7.2.2;
CC   -!- PATHWAY: Metabolic intermediate metabolism; carbamoyl phosphate
CC       degradation; CO(2) and NH(3) from carbamoyl phosphate: step 1/1.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the carbamate kinase family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAC12471.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AL445067; CAC12471.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_010901757.1; NC_002578.1.
DR   AlphaFoldDB; Q9HII9; -.
DR   SMR; Q9HII9; -.
DR   STRING; 273075.Ta1350m; -.
DR   EnsemblBacteria; CAC12471; CAC12471; CAC12471.
DR   GeneID; 1457100; -.
DR   KEGG; tac:Ta1350; -.
DR   eggNOG; arCOG00863; Archaea.
DR   HOGENOM; CLU_076278_0_0_2; -.
DR   OMA; QPMDVAG; -.
DR   OrthoDB; 77437at2157; -.
DR   UniPathway; UPA00996; UER00366.
DR   Proteomes; UP000001024; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008804; F:carbamate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006525; P:arginine metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0035975; P:carbamoyl phosphate catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd04235; AAK_CK; 1.
DR   Gene3D; 3.40.1160.10; -; 1.
DR   InterPro; IPR036393; AceGlu_kinase-like_sf.
DR   InterPro; IPR001048; Asp/Glu/Uridylate_kinase.
DR   InterPro; IPR003964; Carb_kinase.
DR   PANTHER; PTHR30409; PTHR30409; 1.
DR   Pfam; PF00696; AA_kinase; 1.
DR   PIRSF; PIRSF000723; Carbamate_kin; 1.
DR   SUPFAM; SSF53633; SSF53633; 1.
DR   TIGRFAMs; TIGR00746; arcC; 1.
PE   3: Inferred from homology;
KW   Arginine metabolism; ATP-binding; Cytoplasm; Kinase; Nucleotide-binding;
KW   Reference proteome; Transferase.
FT   CHAIN           1..305
FT                   /note="Carbamate kinase"
FT                   /id="PRO_0000185143"
SQ   SEQUENCE   305 AA;  33947 MW;  6124CB5AE6F2E33A CRC64;
     MSRIVIALGG NALLQNGEKR DYETQYEHAY KTFESLRFVT EDNEVVITHG NGPQVGDIQQ
     SHDISGIGAY LHQSVAMSQG YIGEILANAY TNIKTKYNLR KNIFTIITRV LVDENDPAFS
     NPEKPIGRYY SDAEVEEARK NGWIMKKFRD GWRRVVPSPD PRQILEEPVI EYLLHNGNLP
     IAVGGGGVPV VRKGEQIHGI DAVIDKDLAS SVLATAIRAD FLMILTDVDN VYVNYGKPDQ
     KGLHEVHVEE IEKYLKEGQF GEGSMKPKVM AAIRFIKNGG KKAFITSIEN SMNALSGRSG
     TIIVR