ID   LACE_RHIRD              Reviewed;         422 AA.
AC   P29822;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Lactose-binding protein;
DE            Short=LBP;
DE   Flags: Precursor;
GN   Name=lacE;
OS   Rhizobium radiobacter (Agrobacterium tumefaciens) (Agrobacterium
OS   radiobacter).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium;
OC   Agrobacterium tumefaciens complex.
OX   NCBI_TaxID=358;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=AR50;
RX   PubMed=1630315; DOI=10.1111/j.1365-2958.1992.tb01348.x;
RA   Williams S.G., Greenwood J.A., Jones C.W.;
RT   "Molecular analysis of the lac operon encoding the binding-protein-
RT   dependent lactose transport system and beta-galactosidase in Agrobacterium
RT   radiobacter.";
RL   Mol. Microbiol. 6:1755-1768(1992).
RN   [2]
RP   PROTEIN SEQUENCE OF 29-47, AND CHARACTERIZATION.
RX   PubMed=2318800; DOI=10.1128/jb.172.4.1703-1710.1990;
RA   Greenwood J.A., Cornish A., Jones C.W.;
RT   "Binding-protein-dependent lactose transport in Agrobacterium
RT   radiobacter.";
RL   J. Bacteriol. 172:1703-1710(1990).
CC   -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC       lactose.
CC   -!- SUBCELLULAR LOCATION: Periplasm.
CC   -!- INDUCTION: By lactose and various galactosides, and subject to
CC       catabolite repression by glucose, galactose and succinate. In strain
CC       AR50 the expression of the lac operon is constitutive.
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein 1 family.
CC       {ECO:0000305}.
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DR   EMBL; X66596; CAA47161.1; -; Genomic_DNA.
DR   PIR; S25247; JGAGLR.
DR   AlphaFoldDB; P29822; -.
DR   SMR; P29822; -.
DR   TCDB; 3.A.1.1.4; the atp-binding cassette (abc) superfamily.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   InterPro; IPR006059; SBP.
DR   Pfam; PF13416; SBP_bac_8; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Periplasm; Signal; Sugar transport; Transport.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000269|PubMed:2318800"
FT   CHAIN           29..422
FT                   /note="Lactose-binding protein"
FT                   /id="PRO_0000031693"
FT   REGION          246..277
FT                   /note="Lactose-binding"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   422 AA;  45904 MW;  23B6CBCF4BB4135A CRC64;
     MDYSRLLKRS VSAALTAAAL LCSTAAFAGE VTIWCWDPNF NVAIMKEAAE RYTAKHPDTT
     FNIVDFAKAD VEQKLQTGLA SGMTDTLPDI VLIEDYGAQK YLQSFPGSFA ALTDKIDFSG
     FAKYKVDLMT LEGQVYGVPF DSGVTGLYYR TDYLEQAGFK PEDMQNLTWD RFIEIGKEVK
     AKTGHEMMAL DANDGGLIRI MMQSGGQWYF NEDGSLNITG NAALKAALET QARIVNERVA
     KPTSGSNDGI RALTSGDVAS VLRGVWITGT VKSQPDQAGK WALTAIPKLN IEGATAASNL
     GGSSWYVLEA SAEKDEAIDF LNEIYAKDLD FYQKILTERG AVGSLLAART GEAYQKPDDF
     FGGQTVWQNF ADWLVQVPAV NYGIFTNELD TAVTANFPAL VKGTPVDEVL KAIEDQAAGQ
     IQ