ID   LACT2_CAEEL             Reviewed;         473 AA.
AC   Q09621;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=Beta-lactamase domain-containing protein 2;
GN   Name=lact-2; ORFNames=ZK945.1;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; Z48544; CAA88435.1; -; Genomic_DNA.
DR   PIR; T28118; T28118.
DR   RefSeq; NP_496176.1; NM_063775.4.
DR   AlphaFoldDB; Q09621; -.
DR   SMR; Q09621; -.
DR   MEROPS; S12.A11; -.
DR   EPD; Q09621; -.
DR   PaxDb; Q09621; -.
DR   PeptideAtlas; Q09621; -.
DR   EnsemblMetazoa; ZK945.1.1; ZK945.1.1; WBGene00014164.
DR   GeneID; 174570; -.
DR   KEGG; cel:CELE_ZK945.1; -.
DR   CTD; 174570; -.
DR   WormBase; ZK945.1; CE01731; WBGene00014164; lact-2.
DR   eggNOG; ENOG502RZX2; Eukaryota.
DR   HOGENOM; CLU_035614_1_0_1; -.
DR   InParanoid; Q09621; -.
DR   OMA; EFPGTNA; -.
DR   OrthoDB; 1268012at2759; -.
DR   PhylomeDB; Q09621; -.
DR   PRO; PR:Q09621; -.
DR   Proteomes; UP000001940; Chromosome II.
DR   Bgee; WBGene00014164; Expressed in larva and 3 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.710.10; -; 1.
DR   InterPro; IPR001466; Beta-lactam-related.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   Pfam; PF00144; Beta-lactamase; 1.
DR   SUPFAM; SSF56601; SSF56601; 1.
PE   4: Predicted;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..473
FT                   /note="Beta-lactamase domain-containing protein 2"
FT                   /id="PRO_0000065550"
FT   TRANSMEM        26..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        125..143
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   473 AA;  52546 MW;  168F91040768AF54 CRC64;
     MDAMEDKGET EAENVVKLET GSSRRLLIYG IASILAVSGA WLVVATTVDS LACFIEGEMH
     LDNLVGHVAP GYEKVEKVFR RNFADGWERE GASITVYHKD RVIVDLQGGY ADKASGRKWT
     PDTRTVVFST TKAVGAVCVA MLVDRGHISY DDKMSKIWPE FAQNGKENIT IDWLMSHRAG
     LAALDMPITI EDANDFEKMS EVIASQKPNW EPGTKSGYHA ITYGWIVDQI VRRSDPKGRS
     VGRFFKEEVA DVHGIDFHIG LPPSEEHTVS RLSMPSTLHL VREIVHDPRV LIVLAVFNLR
     PPNSIARKIA ANPTWFKLEQ DVNTFNNPTL HAMEQVAALG ITKSRDLARL FSLVQQGKLF
     STELLEKFRA PQVQGIDEVV MTPLPKGHGF LYERHPMGGK KWLVGHPGYG GSTVMMDLED
     GITIAYVSNG LKTGMGELTR TYRHLRDSVF ECLEKQKTGQ SVMIEEAVQA VAA