LAC_CHICK
ID LAC_CHICK Reviewed; 103 AA.
AC P20763;
DT 01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1991, sequence version 1.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=Ig lambda chain C region;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=3107981; DOI=10.1002/j.1460-2075.1987.tb04724.x;
RA Parvari R., Ziv E., Lentner F., Tel-Or S., Burstein Y., Schechter I.;
RT "Analyses of chicken immunoglobulin light chain cDNA clones indicate a few
RT germline V lambda genes and allotypes of the C lambda locus.";
RL EMBO J. 6:97-102(1987).
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DR EMBL; X04768; CAA28461.1; -; Genomic_DNA.
DR PIR; B26167; B26167.
DR AlphaFoldDB; P20763; -.
DR SMR; P20763; -.
DR VEuPathDB; HostDB:geneid_416928; -.
DR HOGENOM; CLU_077975_3_1_1; -.
DR OMA; CQITHEG; -.
DR Reactome; R-GGA-2132263; Creation of classical C3 convertase.
DR Reactome; R-GGA-2132286; Classical antibody-mediated complement activation.
DR Proteomes; UP000000539; Unplaced.
DR GO; GO:0005576; C:extracellular region; TAS:Reactome.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003006; Ig/MHC_CS.
DR InterPro; IPR003597; Ig_C1-set.
DR Pfam; PF07654; C1-set; 1.
DR SMART; SM00407; IGc1; 1.
DR SUPFAM; SSF48726; SSF48726; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS00290; IG_MHC; 1.
PE 4: Predicted;
KW Disulfide bond; Immunoglobulin domain; Reference proteome.
FT CHAIN <1..103
FT /note="Ig lambda chain C region"
FT /id="PRO_0000153606"
FT DOMAIN 6..99
FT /note="Ig-like"
FT DISULFID 28..85
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT DISULFID 103
FT /note="Interchain (with heavy chain)"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT VARIANT 90
FT /note="N -> D"
FT NON_TER 1
SQ SEQUENCE 103 AA; 11361 MW; 77BF341B511B91B2 CRC64;
QPKVAPTITL FPPSKEELNE ATKATLVCLI NDFYPSPVTV DWVIDGSTRS GETTAPQRQS
NSQYMASSYL SLSASDWSSH ETYTCRVTHN GTSITKTLKR SEC