ID   LAFU_VIBPA              Reviewed;         330 AA.
AC   Q03478;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 2.
DT   25-MAY-2022, entry version 127.
DE   RecName: Full=Chemotaxis protein LafU;
GN   Name=lafU; OrderedLocusNames=VPA1557;
OS   Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=223926;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=BB22;
RA   McCarter L.L.;
RL   Submitted (JAN-1995) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RIMD 2210633;
RX   PubMed=12620739; DOI=10.1016/s0140-6736(03)12659-1;
RA   Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K.,
RA   Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S.,
RA   Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T.;
RT   "Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism
RT   distinct from that of V. cholerae.";
RL   Lancet 361:743-749(2003).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-201.
RC   STRAIN=BB22;
RX   PubMed=8501040; DOI=10.1128/jb.175.11.3361-3371.1993;
RA   McCarter L.L., Wright M.E.;
RT   "Identification of genes encoding components of the swarmer cell flagellar
RT   motor and propeller and a sigma factor controlling differentiation of
RT   Vibrio parahaemolyticus.";
RL   J. Bacteriol. 175:3361-3371(1993).
CC   -!- FUNCTION: Probable integral membrane protein required for the rotation
CC       of the flagellar motor. Might be a linker that fastens the torque-
CC       generating machinery to the cell wall.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Single-pass type II membrane
CC       protein.
CC   -!- INDUCTION: Under conditions in which the polar flagellum is not
CC       functional.
CC   -!- SIMILARITY: Belongs to the MotB family. {ECO:0000305}.
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DR   EMBL; U20541; AAA62355.1; -; Genomic_DNA.
DR   EMBL; BA000032; BAC62900.1; -; Genomic_DNA.
DR   EMBL; U52957; AAB07358.1; -; Genomic_DNA.
DR   RefSeq; NP_801067.1; NC_004605.1.
DR   RefSeq; WP_005478256.1; NC_004605.1.
DR   AlphaFoldDB; Q03478; -.
DR   SMR; Q03478; -.
DR   STRING; 223926.28809959; -.
DR   EnsemblBacteria; BAC62900; BAC62900; BAC62900.
DR   GeneID; 1192253; -.
DR   KEGG; vpa:VPA1557; -.
DR   PATRIC; fig|223926.6.peg.4479; -.
DR   eggNOG; COG1360; Bacteria.
DR   HOGENOM; CLU_016890_3_2_6; -.
DR   OMA; FMVLWIM; -.
DR   Proteomes; UP000002493; Chromosome 2.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0097588; P:archaeal or bacterial-type flagellum-dependent cell motility; IEA:UniProtKB-KW.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   CDD; cd07185; OmpA_C-like; 1.
DR   Gene3D; 3.30.1330.60; -; 1.
DR   InterPro; IPR025713; MotB_N_dom.
DR   InterPro; IPR006665; OmpA-like.
DR   InterPro; IPR036737; OmpA-like_sf.
DR   Pfam; PF13677; MotB_plug; 1.
DR   Pfam; PF00691; OmpA; 1.
DR   SUPFAM; SSF103088; SSF103088; 1.
DR   PROSITE; PS51123; OMPA_2; 1.
PE   2: Evidence at transcript level;
KW   Cell inner membrane; Cell membrane; Chemotaxis; Flagellar rotation;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..330
FT                   /note="Chemotaxis protein LafU"
FT                   /id="PRO_0000189591"
FT   TOPO_DOM        1..26
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        27..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        49..330
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          158..278
FT                   /note="OmpA-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00473"
SQ   SEQUENCE   330 AA;  36611 MW;  6DD4A69B11B0D768 CRC64;
     MQKQEHVVFK RAKAHGHDEP HGGAWKVAFA DFMIALMALF LVLWVMQVVD KEERKAIVAH
     LHSSSVFDKS YGNPFDTSQS ISPIDLAQDS SVPSKHNSNH VVSSYFQGDG DGPEINSLVP
     GTFDTQEQLA ALAKVIEEMT AQINAQGNVN VTVTPQGLRI VLQDDYKQHM FSRGGAELTP
     FFEDLLLALA PLFEQVTNPL IISGHTDAIP FKKRFGRQSN WALSASRADV ARKTLVEGGM
     PDDRVMQVTG MSDRALLNPD EPDSSENRRI ELFILTTPAA KVLETLFGNQ DDSELQKAKQ
     KAEFNQPVIR QEVIRYSADA EKQEAKIQAL