ID   LAMB1_YERPE             Reviewed;         423 AA.
AC   Q8ZAS9; Q0WAU6;
DT   27-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT   27-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 140.
DE   RecName: Full=Maltoporin-1;
DE   AltName: Full=Maltose-inducible porin 1;
DE   Flags: Precursor;
GN   Name=lamB1; Synonyms=lamB; OrderedLocusNames=YPO3711, y0032, YP_3073;
OS   Yersinia pestis.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=632;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CO-92 / Biovar Orientalis;
RX   PubMed=11586360; DOI=10.1038/35097083;
RA   Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA   Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA   Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA   Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA   Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA   Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA   Stevens K., Whitehead S., Barrell B.G.;
RT   "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL   Nature 413:523-527(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KIM10+ / Biovar Mediaevalis;
RX   PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA   Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA   Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA   Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA   Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT   "Genome sequence of Yersinia pestis KIM.";
RL   J. Bacteriol. 184:4601-4611(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=91001 / Biovar Mediaevalis;
RX   PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA   Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA   Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA   Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA   Wang J., Huang P., Yang R.;
RT   "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT   avirulent to humans.";
RL   DNA Res. 11:179-197(2004).
CC   -!- FUNCTION: Involved in the transport of maltose and maltodextrins.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Homotrimer formed of three 18-stranded antiparallel beta-
CC       barrels, containing three independent channels. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- INDUCTION: By maltose. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the porin LamB (TC 1.B.3) family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAM83627.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=AAS63244.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AL590842; CAL22298.1; -; Genomic_DNA.
DR   EMBL; AE009952; AAM83627.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AE017042; AAS63244.1; ALT_INIT; Genomic_DNA.
DR   PIR; AG0451; AG0451.
DR   RefSeq; WP_002212092.1; NZ_WUCM01000050.1.
DR   RefSeq; YP_002348592.1; NC_003143.1.
DR   AlphaFoldDB; Q8ZAS9; -.
DR   SMR; Q8ZAS9; -.
DR   STRING; 214092.YPO3711; -.
DR   PaxDb; Q8ZAS9; -.
DR   PRIDE; Q8ZAS9; -.
DR   EnsemblBacteria; AAM83627; AAM83627; y0032.
DR   EnsemblBacteria; AAS63244; AAS63244; YP_3073.
DR   GeneID; 66843941; -.
DR   KEGG; ype:YPO3711; -.
DR   KEGG; ypk:y0032; -.
DR   KEGG; ypm:YP_3073; -.
DR   PATRIC; fig|214092.21.peg.4221; -.
DR   eggNOG; COG4580; Bacteria.
DR   HOGENOM; CLU_032473_4_1_6; -.
DR   OMA; DYGRANA; -.
DR   Proteomes; UP000000815; Chromosome.
DR   Proteomes; UP000001019; Chromosome.
DR   Proteomes; UP000002490; Chromosome.
DR   GO; GO:0045203; C:integral component of cell outer membrane; IBA:GO_Central.
DR   GO; GO:0046930; C:pore complex; IBA:GO_Central.
DR   GO; GO:0015144; F:carbohydrate transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0042958; F:maltodextrin transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015481; F:maltose transporting porin activity; IEA:InterPro.
DR   GO; GO:0015288; F:porin activity; IBA:GO_Central.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0015774; P:polysaccharide transport; IBA:GO_Central.
DR   CDD; cd01346; Maltoporin-like; 1.
DR   Gene3D; 2.40.170.10; -; 1.
DR   HAMAP; MF_01301; LamB; 1.
DR   InterPro; IPR023738; Maltoporin.
DR   InterPro; IPR003192; Porin_LamB.
DR   InterPro; IPR036998; Porin_LamB_sf.
DR   Pfam; PF02264; LamB; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Disulfide bond; Ion transport; Membrane; Porin;
KW   Reference proteome; Signal; Sugar transport; Transmembrane;
KW   Transmembrane beta strand; Transport.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..423
FT                   /note="Maltoporin-1"
FT                   /id="PRO_0000025181"
FT   SITE            30
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000250"
FT   SITE            65
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000250"
FT   SITE            98
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000250"
FT   SITE            142
FT                   /note="Important in sugar transport"
FT                   /evidence="ECO:0000250"
FT   SITE            250
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000250"
FT   SITE            370
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000250"
FT   SITE            422
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000250"
FT   DISULFID        46..62
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   423 AA;  46853 MW;  DD4AA853F3370D01 CRC64;
     MITLRKLPIA LAVAAGVLST QAMAVDFHGY ARSGIGWTAS GGEQQCFQTT GAQSKYRLGN
     ECETYAELKL GQELWKEGDK SFYLDTNVAY SVSQRDDWES TDPAFREANV QGKNLIESLP
     GSTIWAGKRF YQRHDVHMID FYYWDISGPG AGLETIDLGF GKLSVAATRN SESGGSSAWI
     DNQRENAKYT INNVYDVRLA GLETNPGGSL ELGVDYGRAD TQEGYSLAPN ASKDGVMLTA
     EHTQSLMGGF NKFVVQYATD SMTSYNTGHS QGTSVNNNGH LLRVIDHGAI NLAEKWDMMY
     VALYQDIDLD NNNGNTWYSV GVRPMYKWTP IMSTLLEAGY DNVKSQHTGE RNGQYKLTLA
     QQWQAGDSIW SRPAIRVFAT YANWDEKWGY SDTTGVAQDG TIGTNSRGKN NEVTFGAQFE
     AWW