ID   LAMB_ACTSZ              Reviewed;         430 AA.
AC   A6VL53;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Maltoporin {ECO:0000255|HAMAP-Rule:MF_01301};
DE   AltName: Full=Maltose-inducible porin {ECO:0000255|HAMAP-Rule:MF_01301};
DE   Flags: Precursor;
GN   Name=lamB {ECO:0000255|HAMAP-Rule:MF_01301}; OrderedLocusNames=Asuc_0322;
OS   Actinobacillus succinogenes (strain ATCC 55618 / DSM 22257 / CCUG 43843 /
OS   130Z).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Actinobacillus.
OX   NCBI_TaxID=339671;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 55618 / DSM 22257 / CCUG 43843 / 130Z;
RX   PubMed=21118570; DOI=10.1186/1471-2164-11-680;
RA   McKinlay J.B., Laivenieks M., Schindler B.D., McKinlay A.A.,
RA   Siddaramappa S., Challacombe J.F., Lowry S.R., Clum A., Lapidus A.L.,
RA   Burkhart K.B., Harkins V., Vieille C.;
RT   "A genomic perspective on the potential of Actinobacillus succinogenes for
RT   industrial succinate production.";
RL   BMC Genomics 11:680-680(2010).
CC   -!- FUNCTION: Involved in the transport of maltose and maltodextrins.
CC       {ECO:0000255|HAMAP-Rule:MF_01301}.
CC   -!- SUBUNIT: Homotrimer formed of three 18-stranded antiparallel beta-
CC       barrels, containing three independent channels. {ECO:0000255|HAMAP-
CC       Rule:MF_01301}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01301}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01301}.
CC   -!- INDUCTION: By maltose. {ECO:0000255|HAMAP-Rule:MF_01301}.
CC   -!- SIMILARITY: Belongs to the porin LamB (TC 1.B.3) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01301}.
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DR   EMBL; CP000746; ABR73700.1; -; Genomic_DNA.
DR   RefSeq; WP_011978975.1; NC_009655.1.
DR   AlphaFoldDB; A6VL53; -.
DR   SMR; A6VL53; -.
DR   STRING; 339671.Asuc_0322; -.
DR   EnsemblBacteria; ABR73700; ABR73700; Asuc_0322.
DR   KEGG; asu:Asuc_0322; -.
DR   eggNOG; COG4580; Bacteria.
DR   HOGENOM; CLU_032473_4_1_6; -.
DR   OMA; DYGRANA; -.
DR   OrthoDB; 1013077at2; -.
DR   Proteomes; UP000001114; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0042958; F:maltodextrin transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015481; F:maltose transporting porin activity; IEA:InterPro.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   CDD; cd01346; Maltoporin-like; 1.
DR   Gene3D; 2.40.170.10; -; 1.
DR   HAMAP; MF_01301; LamB; 1.
DR   InterPro; IPR023738; Maltoporin.
DR   InterPro; IPR003192; Porin_LamB.
DR   InterPro; IPR036998; Porin_LamB_sf.
DR   Pfam; PF02264; LamB; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Ion transport; Membrane; Porin; Reference proteome;
KW   Signal; Sugar transport; Transmembrane; Transmembrane beta strand;
KW   Transport.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   CHAIN           24..430
FT                   /note="Maltoporin"
FT                   /id="PRO_5000258698"
FT   SITE            29
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   SITE            64
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   SITE            97
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   SITE            142
FT                   /note="Important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   SITE            265
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   SITE            385
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   SITE            429
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
SQ   SEQUENCE   430 AA;  48252 MW;  F49BA8247E8CB88E CRC64;
     MNNKKTLLAV AISGMMFATS AAAVDFHGYA RSGIGWTSGG GEQTALQVNG GGSKYRLGNE
     TETYVELKLG QELFKEGNKS IYLDSNIAYS VDQQVDWEAT DPALREINVQ FKNFAEDLLP
     DATLWAGKRF YQRHDVHMND FYYWDISGPG AGVENINLGF GKLSLAVTRN TEGGATATYG
     TDKVYYIDDN GQIQSRFEER KANVYNDVFD IRLAELNVNP NGKLEIGFDY GNAHTKNGYY
     LEPGASKNGY MITLEHTQGE FFGGFNKFVA QYATDSMTSW NTGHSQGSSV NNNGHMLRLI
     DHGVVQFSPK VEMMYALIYE KTDLDNNQGK TWYSAGIRPM YKWNKTMSTL IELGYDRIKD
     QSSGEKNDLA KITLAQQWQA GDSIWARPAI RVFGTYGRWN DKFNITDRTN AGYKAKDAEF
     VAGVQFEAWW