ID   LAMB_AERHH              Reviewed;         440 AA.
AC   A0KHF6;
DT   12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 2.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Maltoporin {ECO:0000255|HAMAP-Rule:MF_01301};
DE   AltName: Full=Maltose-inducible porin {ECO:0000255|HAMAP-Rule:MF_01301};
DE   Flags: Precursor;
GN   Name=lamB {ECO:0000255|HAMAP-Rule:MF_01301}; OrderedLocusNames=AHA_1166;
OS   Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC
OS   13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=380703;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC
RC   2358 / NCIMB 9240 / NCTC 8049;
RX   PubMed=16980456; DOI=10.1128/jb.00621-06;
RA   Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J., Haft D.H.,
RA   Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M., Jin S.,
RA   Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.;
RT   "Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all trades.";
RL   J. Bacteriol. 188:8272-8282(2006).
CC   -!- FUNCTION: Involved in the transport of maltose and maltodextrins.
CC       {ECO:0000255|HAMAP-Rule:MF_01301}.
CC   -!- SUBUNIT: Homotrimer formed of three 18-stranded antiparallel beta-
CC       barrels, containing three independent channels. {ECO:0000255|HAMAP-
CC       Rule:MF_01301}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01301}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01301}.
CC   -!- INDUCTION: By maltose. {ECO:0000255|HAMAP-Rule:MF_01301}.
CC   -!- SIMILARITY: Belongs to the porin LamB (TC 1.B.3) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01301}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABK39252.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000462; ABK39252.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; YP_855707.1; NC_008570.1.
DR   AlphaFoldDB; A0KHF6; -.
DR   SMR; A0KHF6; -.
DR   STRING; 380703.AHA_1166; -.
DR   EnsemblBacteria; ABK39252; ABK39252; AHA_1166.
DR   KEGG; aha:AHA_1166; -.
DR   PATRIC; fig|380703.7.peg.1172; -.
DR   eggNOG; COG4580; Bacteria.
DR   HOGENOM; CLU_032473_4_1_6; -.
DR   Proteomes; UP000000756; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0042958; F:maltodextrin transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015481; F:maltose transporting porin activity; IEA:InterPro.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   CDD; cd01346; Maltoporin-like; 1.
DR   Gene3D; 2.40.170.10; -; 1.
DR   HAMAP; MF_01301; LamB; 1.
DR   InterPro; IPR023738; Maltoporin.
DR   InterPro; IPR003192; Porin_LamB.
DR   InterPro; IPR036998; Porin_LamB_sf.
DR   Pfam; PF02264; LamB; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Ion transport; Membrane; Porin; Reference proteome;
KW   Signal; Sugar transport; Transmembrane; Transmembrane beta strand;
KW   Transport.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   CHAIN           26..440
FT                   /note="Maltoporin"
FT                   /id="PRO_0000290215"
FT   SITE            31
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   SITE            62
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   SITE            95
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   SITE            154
FT                   /note="Important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   SITE            271
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   SITE            400
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   SITE            439
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
SQ   SEQUENCE   440 AA;  48490 MW;  C9FD1ADD468CAE5F CRC64;
     MKMKAKWLPI AAAVTAALAS QAAFAVDFHG YFRSGVGVSG DGDMVKYNVN KVGRLGNEND
     TYGEVQLGQE VFNKDGKTFY VDSMFAMASN GSNDWEGTGT VCNFDAKQCS GDSDFALRQF
     NVQAKGLLGF APEATLWAGK RYYQRHDIHI SDFYYWNISG AGAGIEGIQA GPGKISFAWI
     RNDRSAKDVF GEYTNTGTSA APNYVKNEDL NVNTLDLRYA GIPLWSEASL EVGAMYALVN
     ETEAQKPLKN NNMKDGVMLT AELTQGILGG FNKTVLQYGT EGYSKTMAFY GDGSWYGAEA
     KDGADGFRII NWGVVPMGNN FEMGHQLVYG VGNEMWDGND KFETMSAVVR PMYKWDDFNK
     TIFEGGYFKD KNKSTNGTTE DDSGYKLTLA QAWSAGSSFW ARPEIRVFAS YLANDEDKKV
     FESGTSKDTY QVGVQAEAWW