ID   LAMB_AERSA              Reviewed;         445 AA.
AC   Q44287; Q44288;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Maltoporin;
DE   AltName: Full=Maltose-inducible porin;
DE   Flags: Precursor;
GN   Name=lamB;
OS   Aeromonas salmonicida.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=645;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Unilever 2862;
RX   PubMed=8405961; DOI=10.1111/j.1574-6968.1993.tb06447.x;
RA   Dodsworth S.J., Bennett A.J., Coleman G.;
RT   "Molecular cloning and nucleotide sequence analysis of the maltose-
RT   inducible porin gene of Aeromonas salmonicida.";
RL   FEMS Microbiol. Lett. 112:191-198(1993).
CC   -!- FUNCTION: Involved in the transport of maltose and maltodextrins.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Homotrimer formed of three 18-stranded antiparallel beta-
CC       barrels, containing three independent channels. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- INDUCTION: By maltose.
CC   -!- SIMILARITY: Belongs to the porin LamB (TC 1.B.3) family. {ECO:0000305}.
CC   -!- CAUTION: It is uncertain whether Met-1 or Met-3 is the initiator.
CC       {ECO:0000305}.
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DR   EMBL; X69464; CAA49223.1; -; Genomic_DNA.
DR   EMBL; X69464; CAA49224.1; -; Genomic_DNA.
DR   PIR; S37779; S37779.
DR   AlphaFoldDB; Q44287; -.
DR   SMR; Q44287; -.
DR   STRING; 1233098.GCA_000315855_03432; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0042958; F:maltodextrin transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015481; F:maltose transporting porin activity; IEA:InterPro.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   CDD; cd01346; Maltoporin-like; 1.
DR   Gene3D; 2.40.170.10; -; 1.
DR   HAMAP; MF_01301; LamB; 1.
DR   InterPro; IPR023738; Maltoporin.
DR   InterPro; IPR003192; Porin_LamB.
DR   InterPro; IPR036998; Porin_LamB_sf.
DR   Pfam; PF02264; LamB; 1.
PE   2: Evidence at transcript level;
KW   Cell outer membrane; Ion transport; Membrane; Porin; Signal;
KW   Sugar transport; Transmembrane; Transmembrane beta strand; Transport.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..445
FT                   /note="Maltoporin"
FT                   /id="PRO_0000025174"
FT   SITE            31
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000250"
FT   SITE            66
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000250"
FT   SITE            99
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000250"
FT   SITE            166
FT                   /note="Important in sugar transport"
FT                   /evidence="ECO:0000250"
FT   SITE            273
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000250"
FT   SITE            402
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000250"
FT   SITE            444
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   445 AA;  48983 MW;  C5FEEE3D20ECA52A CRC64;
     MKMKAKWLPI AAGVTAALAS QAAFAVDFHG YFRSGVGVST DGSMQTGLSD NAKQKVGRLG
     NEADTYGEIQ LGSEVFNKDG KTFYVDSMVA MTSNGSNDWE STESKFQCTS ANGTALDGCE
     NKEDATFALR QFNVQAKGLL GFAPEATLWA GKRYYQRHDV HISDFYYWNI SGRGAGIEGI
     QAGPGKVSFA WVRNDRSGTN VDGTYNDEMN VNTLDLRYAG IPLWQDGSLE VGVDYAIANP
     SDAQKDSANA QYKNAKDGVM LTAELTQGIL GGFNKTVLQY GTEGYSKTFA FWGDRSWYGA
     EAKDGADGFR IINHGVIPMG NSWEMGHQLV YGVGNDMWDT NDKWETMSVV ARPMYKWDDF
     NKTIFEGGYF KDKNKSTNGT SEEDAGYKLT LAQAWSAGSS FWARPEIRVF ASYLAQDKKE
     MKGNAFNNGT ADDTWNFGVQ AEAWW