LAMB_CITK8
ID LAMB_CITK8 Reviewed; 449 AA.
AC A8AN92;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 26-FEB-2008, sequence version 2.
DT 25-MAY-2022, entry version 76.
DE RecName: Full=Maltoporin {ECO:0000255|HAMAP-Rule:MF_01301};
DE AltName: Full=Maltose-inducible porin {ECO:0000255|HAMAP-Rule:MF_01301};
DE Flags: Precursor;
GN Name=lamB {ECO:0000255|HAMAP-Rule:MF_01301}; OrderedLocusNames=CKO_03879;
OS Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Citrobacter.
OX NCBI_TaxID=290338;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-895 / CDC 4225-83 / SGSC4696;
RG The Citrobacter koseri Genome Sequencing Project;
RA McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S.,
RA Latreille P., Courtney L., Wang C., Pepin K., Bhonagiri V., Nash W.,
RA Johnson M., Thiruvilangam P., Wilson R.;
RL Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in the transport of maltose and maltodextrins.
CC {ECO:0000255|HAMAP-Rule:MF_01301}.
CC -!- SUBUNIT: Homotrimer formed of three 18-stranded antiparallel beta-
CC barrels, containing three independent channels. {ECO:0000255|HAMAP-
CC Rule:MF_01301}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC Rule:MF_01301}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01301}.
CC -!- INDUCTION: By maltose. {ECO:0000255|HAMAP-Rule:MF_01301}.
CC -!- SIMILARITY: Belongs to the porin LamB (TC 1.B.3) family.
CC {ECO:0000255|HAMAP-Rule:MF_01301}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABV14955.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; CP000822; ABV14955.1; ALT_INIT; Genomic_DNA.
DR AlphaFoldDB; A8AN92; -.
DR BMRB; A8AN92; -.
DR SMR; A8AN92; -.
DR STRING; 290338.CKO_03879; -.
DR EnsemblBacteria; ABV14955; ABV14955; CKO_03879.
DR KEGG; cko:CKO_03879; -.
DR HOGENOM; CLU_032473_4_1_6; -.
DR Proteomes; UP000008148; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR GO; GO:0042958; F:maltodextrin transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015481; F:maltose transporting porin activity; IEA:InterPro.
DR GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR CDD; cd01346; Maltoporin-like; 1.
DR Gene3D; 2.40.170.10; -; 1.
DR HAMAP; MF_01301; LamB; 1.
DR InterPro; IPR023738; Maltoporin.
DR InterPro; IPR003192; Porin_LamB.
DR InterPro; IPR036998; Porin_LamB_sf.
DR Pfam; PF02264; LamB; 1.
PE 3: Inferred from homology;
KW Cell outer membrane; Ion transport; Membrane; Porin; Reference proteome;
KW Signal; Sugar transport; Transmembrane; Transmembrane beta strand;
KW Transport.
FT SIGNAL 1..24
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT CHAIN 25..449
FT /note="Maltoporin"
FT /id="PRO_0000322011"
FT SITE 30
FT /note="Greasy slide, important in sugar transport"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT SITE 65
FT /note="Greasy slide, important in sugar transport"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT SITE 98
FT /note="Greasy slide, important in sugar transport"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT SITE 142
FT /note="Important in sugar transport"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT SITE 251
FT /note="Greasy slide, important in sugar transport"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT SITE 390
FT /note="Greasy slide, important in sugar transport"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT SITE 448
FT /note="Greasy slide, important in sugar transport"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
SQ SEQUENCE 449 AA; 50401 MW; 756A665FA20F9C65 CRC64;
MITLRKLPLA VAVAAGVMSA QAMAVDFHGY ARSGIGWTGS GGEQQCFQAT GAQSKYRLGN
ECETYAELKL GQEVWKEGDK SFYFDTNVAY SVAQQNDWEA TDPAFREANV QGKNLIDWLP
GSTIWAGKRF YQRHDVHMID FYYWDISGPG AGIENIDLGF GKLSLAATRS QEAGGSYTFS
SQDIYNSSKD TANDVFDVRL AGLETNPDGV LELGVDYGRA NTTDDYRLAD GASKDGWMFT
AEHTQSMLKG YNKFVVQYAT DAMTTQGKGI PQGSYGSTFD IGEGDDQLHY VDRYVNNNGK
LWRILDHGAI SLGDRWDLMY VGMFQKQDLD NDLGTDWWTV GVRPMFKWTP IMSTLLEVGY
DNVKSQQTGD RNNQYKITLA QQWQAGDSIW SRPAIRLFAT YAKWDEKWGY IKDGDNTLRY
AASNNSGFNT TSRGDNDEWS FGAQMEIWW