ID   LAMB_CROS8              Reviewed;         448 AA.
AC   A7MPN7;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   26-FEB-2008, sequence version 2.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Maltoporin {ECO:0000255|HAMAP-Rule:MF_01301};
DE   AltName: Full=Maltose-inducible porin {ECO:0000255|HAMAP-Rule:MF_01301};
DE   Flags: Precursor;
GN   Name=lamB {ECO:0000255|HAMAP-Rule:MF_01301}; OrderedLocusNames=ESA_00083;
OS   Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Cronobacter.
OX   NCBI_TaxID=290339;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-894;
RX   PubMed=20221447; DOI=10.1371/journal.pone.0009556;
RA   Kucerova E., Clifton S.W., Xia X.Q., Long F., Porwollik S., Fulton L.,
RA   Fronick C., Minx P., Kyung K., Warren W., Fulton R., Feng D., Wollam A.,
RA   Shah N., Bhonagiri V., Nash W.E., Hallsworth-Pepin K., Wilson R.K.,
RA   McClelland M., Forsythe S.J.;
RT   "Genome sequence of Cronobacter sakazakii BAA-894 and comparative genomic
RT   hybridization analysis with other Cronobacter species.";
RL   PLoS ONE 5:E9556-E9556(2010).
CC   -!- FUNCTION: Involved in the transport of maltose and maltodextrins.
CC       {ECO:0000255|HAMAP-Rule:MF_01301}.
CC   -!- SUBUNIT: Homotrimer formed of three 18-stranded antiparallel beta-
CC       barrels, containing three independent channels. {ECO:0000255|HAMAP-
CC       Rule:MF_01301}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01301}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01301}.
CC   -!- INDUCTION: By maltose. {ECO:0000255|HAMAP-Rule:MF_01301}.
CC   -!- SIMILARITY: Belongs to the porin LamB (TC 1.B.3) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01301}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABU75388.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000783; ABU75388.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_007888874.1; NC_009778.1.
DR   AlphaFoldDB; A7MPN7; -.
DR   SMR; A7MPN7; -.
DR   EnsemblBacteria; ABU75388; ABU75388; ESA_00083.
DR   GeneID; 56733076; -.
DR   KEGG; esa:ESA_00083; -.
DR   HOGENOM; CLU_032473_4_1_6; -.
DR   OrthoDB; 1013077at2; -.
DR   Proteomes; UP000000260; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0042958; F:maltodextrin transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015481; F:maltose transporting porin activity; IEA:InterPro.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   CDD; cd01346; Maltoporin-like; 1.
DR   Gene3D; 2.40.170.10; -; 1.
DR   HAMAP; MF_01301; LamB; 1.
DR   InterPro; IPR023738; Maltoporin.
DR   InterPro; IPR003192; Porin_LamB.
DR   InterPro; IPR036998; Porin_LamB_sf.
DR   Pfam; PF02264; LamB; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Ion transport; Membrane; Porin; Signal;
KW   Sugar transport; Transmembrane; Transmembrane beta strand; Transport.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   CHAIN           24..448
FT                   /note="Maltoporin"
FT                   /id="PRO_0000322012"
FT   SITE            31
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   SITE            66
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   SITE            99
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   SITE            143
FT                   /note="Important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   SITE            252
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   SITE            385
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   SITE            447
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
SQ   SEQUENCE   448 AA;  49744 MW;  1267CB3D2A30C307 CRC64;
     MMITLRKLPL AVAVMAGIFA AQASAVDFKG YARSGIGWTG SGGEQQCFQA TGAGAKYRLG
     NECETYAELK LGQEVWKEGD KSFYFDTNVA YSVAQQNDWE ATSPAFREAN VQGKNLIDAL
     PGSTIWAGKR FYQRHDVHMI DFYYWDISGP GAGIENVDLG FGKLSVAATR SSEAGGSATF
     QSDSIYDYNK STANDVFDVR LGSLEVNPGG TLELGVDYGR ANARDDYYLA DDATKDGWMF
     TAEHVQTIGT GFNKFVVQYA TDALTSQGKG LSQGSGIGIS DTDPKFAYAQ NNNGHMLRLI
     DHGSISMGDR WDMMYVGMYQ DIDWDNNNGT RWWTVGVRPM FKWTPIMSTL LEVGYDNVKS
     QRTDETNNQY KITLAQQWQA GDSIWSRPAL RVFATYAKWD EKWGYDKTGN PSNNANYGYA
     VKDGFNGGSF GRGDNDEWTF GAQMEIWW