ID   LAMB_PECAS              Reviewed;         435 AA.
AC   Q6D2C3;
DT   12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Maltoporin {ECO:0000255|HAMAP-Rule:MF_01301};
DE   AltName: Full=Maltose-inducible porin {ECO:0000255|HAMAP-Rule:MF_01301};
DE   Flags: Precursor;
GN   Name=lamB {ECO:0000255|HAMAP-Rule:MF_01301}; OrderedLocusNames=ECA3173;
OS   Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia
OS   carotovora subsp. atroseptica).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Pectobacterium.
OX   NCBI_TaxID=218491;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SCRI 1043 / ATCC BAA-672;
RX   PubMed=15263089; DOI=10.1073/pnas.0402424101;
RA   Bell K.S., Sebaihia M., Pritchard L., Holden M.T.G., Hyman L.J.,
RA   Holeva M.C., Thomson N.R., Bentley S.D., Churcher L.J.C., Mungall K.,
RA   Atkin R., Bason N., Brooks K., Chillingworth T., Clark K., Doggett J.,
RA   Fraser A., Hance Z., Hauser H., Jagels K., Moule S., Norbertczak H.,
RA   Ormond D., Price C., Quail M.A., Sanders M., Walker D., Whitehead S.,
RA   Salmond G.P.C., Birch P.R.J., Parkhill J., Toth I.K.;
RT   "Genome sequence of the enterobacterial phytopathogen Erwinia carotovora
RT   subsp. atroseptica and characterization of virulence factors.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:11105-11110(2004).
CC   -!- FUNCTION: Involved in the transport of maltose and maltodextrins.
CC       {ECO:0000255|HAMAP-Rule:MF_01301}.
CC   -!- SUBUNIT: Homotrimer formed of three 18-stranded antiparallel beta-
CC       barrels, containing three independent channels. {ECO:0000255|HAMAP-
CC       Rule:MF_01301}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01301}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01301}.
CC   -!- INDUCTION: By maltose. {ECO:0000255|HAMAP-Rule:MF_01301}.
CC   -!- SIMILARITY: Belongs to the porin LamB (TC 1.B.3) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01301}.
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DR   EMBL; BX950851; CAG76071.1; -; Genomic_DNA.
DR   RefSeq; WP_011094695.1; NC_004547.2.
DR   AlphaFoldDB; Q6D2C3; -.
DR   SMR; Q6D2C3; -.
DR   STRING; 218491.ECA3173; -.
DR   EnsemblBacteria; CAG76071; CAG76071; ECA3173.
DR   GeneID; 57209858; -.
DR   KEGG; eca:ECA3173; -.
DR   PATRIC; fig|218491.5.peg.3212; -.
DR   eggNOG; COG4580; Bacteria.
DR   HOGENOM; CLU_032473_4_1_6; -.
DR   OMA; YYTYASW; -.
DR   OrthoDB; 1013077at2; -.
DR   Proteomes; UP000007966; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0042958; F:maltodextrin transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015481; F:maltose transporting porin activity; IEA:InterPro.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   CDD; cd01346; Maltoporin-like; 1.
DR   Gene3D; 2.40.170.10; -; 1.
DR   HAMAP; MF_01301; LamB; 1.
DR   InterPro; IPR023738; Maltoporin.
DR   InterPro; IPR003192; Porin_LamB.
DR   InterPro; IPR036998; Porin_LamB_sf.
DR   Pfam; PF02264; LamB; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Ion transport; Membrane; Porin; Reference proteome;
KW   Signal; Sugar transport; Transmembrane; Transmembrane beta strand;
KW   Transport.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   CHAIN           24..435
FT                   /note="Maltoporin"
FT                   /id="PRO_0000290216"
FT   SITE            29
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   SITE            60
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   SITE            434
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
SQ   SEQUENCE   435 AA;  48922 MW;  59A53419A4FBFC53 CRC64;
     MKRKLLTTSI ALSLAMLATP SYSVDFSGYF RSGVGVSNHG KQQTADKSYV GRLGNEDDTY
     GEIQLGQQLY NENGKTFYFD SMISMFSNSS NDNETTKNDD AEFGLRQLNL QAKGFVPGLP
     DATVWAGKRY YQRHDLHIID TKYWNISGAG AGIENVKAGE GAFSFAWIRA DAENMDVDCG
     NSLNSQECSS REDTYNDLNI NYLDARYAGW KPWDGAWTEF GISYAMPNEA DTQKNIFLAE
     GQKFDPKNSM MITGELSHYF SGLKSNQKLV LQYADKGLAH NMVDQGGGWY DVWSINDSAK
     GYRVIQAGDL PITDHISLSH VLTYGKADEI SRWRDSTELL SAVGRGQYAW TKNQKTYLEA
     GTYQKKDSWK AGTETKYSGQ KYTLAHAFSA DIPMLTRPEL RFFVSYLDGG NENRNRFNDD
     RSNTVNFGIQ AEAWW