ID   LAMB_VIBCH              Reviewed;         412 AA.
AC   Q56652; Q9KKS2;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 122.
DE   RecName: Full=Maltoporin;
DE   AltName: Full=Maltose-inducible porin;
DE   AltName: Full=Outer membrane protein S;
DE   Flags: Precursor;
GN   Name=lamB; Synonyms=ompS; OrderedLocusNames=VC_A1028;
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=X28214;
RX   PubMed=7934851; DOI=10.1111/j.1365-2958.1993.tb00960.x;
RA   Lang H., Palva E.T.;
RT   "The ompS gene of Vibrio cholerae encodes a growth-phase-dependent
RT   maltoporin.";
RL   Mol. Microbiol. 10:891-901(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
CC   -!- FUNCTION: Involved in the transport of maltose and maltodextrins.
CC   -!- SUBUNIT: Homotrimer formed of three 18-stranded antiparallel beta-
CC       barrels, containing three independent channels. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- INDUCTION: By maltose.
CC   -!- SIMILARITY: Belongs to the porin LamB (TC 1.B.3) family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAF96924.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X69379; CAA49176.1; -; Genomic_DNA.
DR   EMBL; AE003853; AAF96924.1; ALT_INIT; Genomic_DNA.
DR   PIR; C82388; C82388.
DR   PIR; S39869; S39869.
DR   RefSeq; NP_233412.1; NC_002506.1.
DR   RefSeq; WP_000757932.1; NZ_LT906615.1.
DR   AlphaFoldDB; Q56652; -.
DR   SMR; Q56652; -.
DR   STRING; 243277.VC_A1028; -.
DR   DNASU; 2612207; -.
DR   EnsemblBacteria; AAF96924; AAF96924; VC_A1028.
DR   GeneID; 57742381; -.
DR   KEGG; vch:VC_A1028; -.
DR   PATRIC; fig|243277.26.peg.3633; -.
DR   eggNOG; COG4580; Bacteria.
DR   HOGENOM; CLU_032473_4_1_6; -.
DR   OMA; DYGRANA; -.
DR   Proteomes; UP000000584; Chromosome 2.
DR   GO; GO:0045203; C:integral component of cell outer membrane; IBA:GO_Central.
DR   GO; GO:0046930; C:pore complex; IBA:GO_Central.
DR   GO; GO:0015144; F:carbohydrate transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0042958; F:maltodextrin transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015481; F:maltose transporting porin activity; IEA:InterPro.
DR   GO; GO:0015288; F:porin activity; IBA:GO_Central.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0015774; P:polysaccharide transport; IBA:GO_Central.
DR   CDD; cd01346; Maltoporin-like; 1.
DR   Gene3D; 2.40.170.10; -; 1.
DR   HAMAP; MF_01301; LamB; 1.
DR   InterPro; IPR023738; Maltoporin.
DR   InterPro; IPR003192; Porin_LamB.
DR   InterPro; IPR036998; Porin_LamB_sf.
DR   Pfam; PF02264; LamB; 1.
PE   2: Evidence at transcript level;
KW   Cell outer membrane; Ion transport; Membrane; Porin; Reference proteome;
KW   Signal; Sugar transport; Transmembrane; Transmembrane beta strand;
KW   Transport.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..412
FT                   /note="Maltoporin"
FT                   /id="PRO_0000025183"
FT   SITE            28
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000250"
FT   SITE            60
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000250"
FT   SITE            92
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000250"
FT   SITE            136
FT                   /note="Important in sugar transport"
FT                   /evidence="ECO:0000250"
FT   SITE            227
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000250"
FT   SITE            374
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000250"
FT   SITE            411
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   412 AA;  44537 MW;  D5DEFA1E41C8AF34 CRC64;
     MKKVSVIAAA VAATLAAGSA FAVDFNGYFR AGTGISGNGN ADQAVNKAGT GRLGNENDNY
     YEFGFAEELK TGEQTWKVES MIAQGNSGAN GWEDGDFNVA QFNVQAKGLL ASDQEAVMWA
     GKRYYQRKDI HITDFYFLNT SGTGGGIENL SVGNQKLSVA LVQDGDNTNS SGYIFDARLA
     NIGLWENASL ELAMAYNFAT EKDSKNEVAD DGVLVSAILH QGLSNGFNQT VFQYGTAGYG
     AQAANFWGAG SYYARGTEAF NDASGFRLLN WGVINLGENW EMGHQLAYLA GSDIGGQFGG
     DGANKNTYTG KSFDIDQYSV VVRPMYKWND TMRTVFEAGY NAGEKISNGG LATEDFGNAK
     FTVAQAWAMG DSFWARPELR VYGTYLLDTE NDKAFGDDDT EFVVGIQVEA WW