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LAMB_VIBCM
ID   LAMB_VIBCM              Reviewed;         416 AA.
AC   C3LWU0;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2009, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Maltoporin {ECO:0000255|HAMAP-Rule:MF_01301};
DE   AltName: Full=Maltose-inducible porin {ECO:0000255|HAMAP-Rule:MF_01301};
DE   Flags: Precursor;
GN   Name=lamB {ECO:0000255|HAMAP-Rule:MF_01301}; OrderedLocusNames=VCM66_A0986;
OS   Vibrio cholerae serotype O1 (strain M66-2).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=579112;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M66-2;
RX   PubMed=19115014; DOI=10.1371/journal.pone.0004053;
RA   Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J.,
RA   Wang W., Wang J., Qian W., Li D., Wang L.;
RT   "A recalibrated molecular clock and independent origins for the cholera
RT   pandemic clones.";
RL   PLoS ONE 3:E4053-E4053(2008).
CC   -!- FUNCTION: Involved in the transport of maltose and maltodextrins.
CC       {ECO:0000255|HAMAP-Rule:MF_01301}.
CC   -!- SUBUNIT: Homotrimer formed of three 18-stranded antiparallel beta-
CC       barrels, containing three independent channels. {ECO:0000255|HAMAP-
CC       Rule:MF_01301}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01301}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01301}.
CC   -!- INDUCTION: By maltose. {ECO:0000255|HAMAP-Rule:MF_01301}.
CC   -!- SIMILARITY: Belongs to the porin LamB (TC 1.B.3) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01301}.
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DR   EMBL; CP001234; ACP07945.1; -; Genomic_DNA.
DR   RefSeq; WP_001882819.1; NC_012580.1.
DR   AlphaFoldDB; C3LWU0; -.
DR   SMR; C3LWU0; -.
DR   EnsemblBacteria; ACP07945; ACP07945; VCM66_A0986.
DR   KEGG; vcm:VCM66_A0986; -.
DR   HOGENOM; CLU_032473_4_1_6; -.
DR   OMA; DYGRANA; -.
DR   Proteomes; UP000001217; Chromosome II.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0042958; F:maltodextrin transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015481; F:maltose transporting porin activity; IEA:InterPro.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   CDD; cd01346; Maltoporin-like; 1.
DR   Gene3D; 2.40.170.10; -; 1.
DR   HAMAP; MF_01301; LamB; 1.
DR   InterPro; IPR023738; Maltoporin.
DR   InterPro; IPR003192; Porin_LamB.
DR   InterPro; IPR036998; Porin_LamB_sf.
DR   Pfam; PF02264; LamB; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Ion transport; Membrane; Porin; Signal;
KW   Sugar transport; Transmembrane; Transmembrane beta strand; Transport.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   CHAIN           27..416
FT                   /note="Maltoporin"
FT                   /id="PRO_1000165295"
FT   SITE            32
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   SITE            64
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   SITE            96
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   SITE            140
FT                   /note="Important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   SITE            231
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   SITE            378
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
FT   SITE            415
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01301"
SQ   SEQUENCE   416 AA;  45011 MW;  168B2BA308E5B26D CRC64;
     MELTMKKVSV IAAAVAATLA AGSAFAVDFN GYFRAGTGIS GNGNADQAVN KAGTGRLGNE
     NDNYYEFGFA EELKTGEQTW KVESMIAQGN SGANGWEDGD FNVAQFNVQA KGLLASDQEA
     VMWAGKRYYQ RKDIHITDFY FLNTSGTGGG IENLSVGNQK LSVALVQDGD NTNSSGYIFD
     ARLANIGLWE NASLELAMAY NFATEKDSKN EVADDGVLVS AILHQGLSNG FNQTVFQYGT
     AGYGAQAANF WGAGSYYARG TEAFNDASGF RLLNWGVINL GENWEMGHQL AYLAGSDIGG
     QFGGDGANKN TYTGKSFDID QYSVVVRPMY KWNDTMRTVF EAGYNAGEKI SNGGLATEDF
     GNAKFTVAQA WAMGDSFWAR PELRVYGTYL LDTENDKAFG DDDTEFVVGI QVEAWW
 
 
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