ID   LAMB_VIBPA              Reviewed;         432 AA.
AC   P59494;
DT   04-APR-2003, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2003, sequence version 1.
DT   25-MAY-2022, entry version 102.
DE   RecName: Full=Maltoporin;
DE   AltName: Full=Maltose-inducible porin;
DE   Flags: Precursor;
GN   Name=lamB; OrderedLocusNames=VPA1644;
OS   Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=223926;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RIMD 2210633;
RX   PubMed=12620739; DOI=10.1016/s0140-6736(03)12659-1;
RA   Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K.,
RA   Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S.,
RA   Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T.;
RT   "Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism
RT   distinct from that of V. cholerae.";
RL   Lancet 361:743-749(2003).
CC   -!- FUNCTION: Involved in the transport of maltose and maltodextrins.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Homotrimer formed of three 18-stranded antiparallel beta-
CC       barrels, containing three independent channels. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- INDUCTION: By maltose. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the porin LamB (TC 1.B.3) family. {ECO:0000305}.
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DR   EMBL; BA000032; BAC62987.1; -; Genomic_DNA.
DR   RefSeq; NP_801154.1; NC_004605.1.
DR   RefSeq; WP_005458362.1; NC_004605.1.
DR   AlphaFoldDB; P59494; -.
DR   SMR; P59494; -.
DR   STRING; 223926.28810046; -.
DR   EnsemblBacteria; BAC62987; BAC62987; BAC62987.
DR   GeneID; 1192340; -.
DR   KEGG; vpa:VPA1644; -.
DR   PATRIC; fig|223926.6.peg.4563; -.
DR   eggNOG; COG4580; Bacteria.
DR   HOGENOM; CLU_032473_4_1_6; -.
DR   OMA; DYGRANA; -.
DR   Proteomes; UP000002493; Chromosome 2.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0042958; F:maltodextrin transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015481; F:maltose transporting porin activity; IEA:InterPro.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   CDD; cd01346; Maltoporin-like; 1.
DR   Gene3D; 2.40.170.10; -; 1.
DR   HAMAP; MF_01301; LamB; 1.
DR   InterPro; IPR023738; Maltoporin.
DR   InterPro; IPR003192; Porin_LamB.
DR   InterPro; IPR036998; Porin_LamB_sf.
DR   Pfam; PF02264; LamB; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Ion transport; Membrane; Porin; Reference proteome;
KW   Signal; Sugar transport; Transmembrane; Transmembrane beta strand;
KW   Transport.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..432
FT                   /note="Maltoporin"
FT                   /id="PRO_0000025184"
FT   SITE            28
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000250"
FT   SITE            60
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000250"
FT   SITE            93
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000250"
FT   SITE            154
FT                   /note="Important in sugar transport"
FT                   /evidence="ECO:0000250"
FT   SITE            266
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000250"
FT   SITE            390
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000250"
FT   SITE            431
FT                   /note="Greasy slide, important in sugar transport"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   432 AA;  46963 MW;  8ECB74034AF7EDD0 CRC64;
     MKKVSVIAAA VAATLAAGSA FAVDFHGYMR AGVGVNADGG QQLTFEKNKV GRLGNESDIY
     GEIQLGKEVY NNNGKTFYVD SMLAMTSNGS NDWEGTAANC GLDGTKVKCV DDAQFALRQF
     NVQAKGVLNF APEATLWAGK RYYQRHDIHI SDFYYWNISG AGAGVEGIEA GPGKLSFAWV
     RNDRNDNFNS GMGSGDTPDV GNGGSVNVNT LDVRYAGIPV WENGSLEVGL DYALVNETED
     ASKAAKDAKD GVMFTAELTQ GLDSGFNKTV FQYGTEGYSK AFAFYGDGSW YGAEARDGAS
     GYRFINWGVI GLGDNWELGH QLVYGVGEDM WAADHKWEAM SAVVRPVFKW DDNHKTIFEA
     GYAIDDNDGD ENKYGKLTVA QAWSAGSSFW ARPEIRLYAS YLTADKADNS NTFDSGRSDD
     TFQFGVQAEA WW