LAMB_YEREN
ID LAMB_YEREN Reviewed; 400 AA.
AC Q56850;
DT 15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 25-MAY-2022, entry version 90.
DE RecName: Full=Maltoporin;
DE AltName: Full=Maltose-inducible porin;
DE Flags: Fragment;
GN Name=lamB;
OS Yersinia enterocolitica.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=630;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=7702622; DOI=10.1006/bbrc.1995.1423;
RA Lang H., Ferenci T.;
RT "Sequence alignment and structural modelling of the LamB glycoporin
RT family.";
RL Biochem. Biophys. Res. Commun. 208:927-934(1995).
CC -!- FUNCTION: Involved in the transport of maltose and maltodextrins.
CC {ECO:0000250}.
CC -!- SUBUNIT: Homotrimer formed of three 18-stranded antiparallel beta-
CC barrels, containing three independent channels. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- INDUCTION: By maltose. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the porin LamB (TC 1.B.3) family. {ECO:0000305}.
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DR EMBL; U16150; AAA70348.1; -; Genomic_DNA.
DR AlphaFoldDB; Q56850; -.
DR SMR; Q56850; -.
DR STRING; 1443113.LC20_00442; -.
DR eggNOG; COG4580; Bacteria.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR GO; GO:0034219; P:carbohydrate transmembrane transport; IEA:InterPro.
DR GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR CDD; cd01346; Maltoporin-like; 1.
DR Gene3D; 2.40.170.10; -; 1.
DR InterPro; IPR003192; Porin_LamB.
DR InterPro; IPR036998; Porin_LamB_sf.
DR Pfam; PF02264; LamB; 1.
PE 3: Inferred from homology;
KW Cell outer membrane; Disulfide bond; Ion transport; Membrane; Porin;
KW Sugar transport; Transmembrane; Transmembrane beta strand; Transport.
FT CHAIN <1..>400
FT /note="Maltoporin"
FT /id="PRO_0000196261"
FT TRANSMEM <1..9
FT /note="Beta stranded"
FT /evidence="ECO:0000250"
FT TOPO_DOM 10..38
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 39..52
FT /note="Beta stranded"
FT /evidence="ECO:0000250"
FT TOPO_DOM 53..54
FT /note="Periplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 55..67
FT /note="Beta stranded"
FT /evidence="ECO:0000250"
FT TOPO_DOM 68..78
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 79..89
FT /note="Beta stranded"
FT /evidence="ECO:0000250"
FT TOPO_DOM 90..96
FT /note="Periplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 97..104
FT /note="Beta stranded"
FT /evidence="ECO:0000250"
FT TOPO_DOM 105..122
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 123..133
FT /note="Beta stranded"
FT /evidence="ECO:0000250"
FT TOPO_DOM 134..135
FT /note="Periplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 136..147
FT /note="Beta stranded"
FT /evidence="ECO:0000250"
FT TOPO_DOM 148..164
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 165..178
FT /note="Beta stranded"
FT /evidence="ECO:0000250"
FT TOPO_DOM 179..182
FT /note="Periplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 183..195
FT /note="Beta stranded"
FT /evidence="ECO:0000250"
FT TOPO_DOM 196..207
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 208..221
FT /note="Beta stranded"
FT /evidence="ECO:0000250"
FT TOPO_DOM 222..223
FT /note="Periplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 224..236
FT /note="Beta stranded"
FT /evidence="ECO:0000250"
FT TOPO_DOM 237..252
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 253..267
FT /note="Beta stranded"
FT /evidence="ECO:0000250"
FT TOPO_DOM 268..269
FT /note="Periplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 270..285
FT /note="Beta stranded"
FT /evidence="ECO:0000250"
FT TOPO_DOM 286..288
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 289..303
FT /note="Beta stranded"
FT /evidence="ECO:0000250"
FT TOPO_DOM 304..306
FT /note="Periplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 307..322
FT /note="Beta stranded"
FT /evidence="ECO:0000250"
FT TOPO_DOM 323..325
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 326..341
FT /note="Beta stranded"
FT /evidence="ECO:0000250"
FT TOPO_DOM 342..348
FT /note="Periplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 349..363
FT /note="Beta stranded"
FT /evidence="ECO:0000250"
FT TOPO_DOM 364..388
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 389..399
FT /note="Beta stranded"
FT /evidence="ECO:0000250"
FT TOPO_DOM 400
FT /note="Periplasmic"
FT /evidence="ECO:0000250"
FT SITE 5
FT /note="Greasy slide, important in sugar transport"
FT /evidence="ECO:0000250"
FT SITE 40
FT /note="Greasy slide, important in sugar transport"
FT /evidence="ECO:0000250"
FT SITE 73
FT /note="Greasy slide, important in sugar transport"
FT /evidence="ECO:0000250"
FT SITE 117
FT /note="Important in sugar transport"
FT /evidence="ECO:0000250"
FT SITE 225
FT /note="Greasy slide, important in sugar transport"
FT /evidence="ECO:0000250"
FT SITE 346
FT /note="Greasy slide, important in sugar transport"
FT /evidence="ECO:0000250"
FT DISULFID 21..37
FT /evidence="ECO:0000250"
FT NON_TER 1
FT NON_TER 400
SQ SEQUENCE 400 AA; 44545 MW; F88A531EA6F56AE8 CRC64;
HFHGYARSGI GWTGSGGEQQ CFKTTGAQSK YRLGNECETY AELKLGQELW KEGDKSFYLD
TNVAYSVSQR DDWESTDPAF REANVQGKNL IESFPGSTMW AGKRFYQRHD VHMIDFYYWD
ISGPGAGLEA IDLGFGKLSV AATRNSEAGG SSAWINNQRK DADKTINDVY DIRLAGLETN
PGGSLEFGVD YGRANTQDDY SLAPNASKDG VLLTAEHTQS MMGGFNKFVV QYATDSMTSW
NSGHSQGTSV NNNGHMLRVI DHGAINLAEK WDMMYVALYQ DTDWDNNNGT TWYSVGVRPM
LQMELPIMST LLEIGYNNVK SQRTGKRNGQ YKLTLAQQWQ AGDSIWSRPA TRVFATYANW
DEKWGYNNVD KSPDNGLAQN GTIGTDSRGK SNECTFGAQF
