ID   LANC3_DROME             Reviewed;         419 AA.
AC   Q9Y0Y7; A4V498;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   03-AUG-2022, entry version 134.
DE   RecName: Full=LanC-like protein 3 homolog;
GN   ORFNames=CG2061;
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley;
RX   PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA   Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA   Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA   George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA   Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA   Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA   Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA   An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA   Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA   Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA   Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA   Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA   Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA   Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA   Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA   Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA   Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA   Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA   Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA   Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA   Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA   Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA   McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA   Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA   Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA   Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA   Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA   Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA   Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA   Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA   Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA   Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA   Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA   Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA   Venter J.C.;
RT   "The genome sequence of Drosophila melanogaster.";
RL   Science 287:2185-2195(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=Berkeley;
RX   PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA   Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA   Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA   Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA   Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA   Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA   Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT   "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT   review.";
RL   Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Berkeley; TISSUE=Embryo;
RX   PubMed=12537569; DOI=10.1186/gb-2002-3-12-research0080;
RA   Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A.,
RA   Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M.,
RA   Celniker S.E.;
RT   "A Drosophila full-length cDNA resource.";
RL   Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002).
CC   -!- SIMILARITY: Belongs to the LanC-like protein family. {ECO:0000305}.
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DR   EMBL; AE014298; AAF47995.1; -; Genomic_DNA.
DR   EMBL; AE014298; AAN09280.1; -; Genomic_DNA.
DR   EMBL; AF145689; AAD38664.1; -; mRNA.
DR   RefSeq; NP_001259437.1; NM_001272508.1.
DR   RefSeq; NP_572682.1; NM_132454.5.
DR   RefSeq; NP_727485.1; NM_167264.2.
DR   AlphaFoldDB; Q9Y0Y7; -.
DR   SMR; Q9Y0Y7; -.
DR   BioGRID; 58457; 7.
DR   IntAct; Q9Y0Y7; 4.
DR   STRING; 7227.FBpp0073286; -.
DR   PaxDb; Q9Y0Y7; -.
DR   PRIDE; Q9Y0Y7; -.
DR   DNASU; 32042; -.
DR   EnsemblMetazoa; FBtr0073429; FBpp0073285; FBgn0027498.
DR   EnsemblMetazoa; FBtr0073431; FBpp0073287; FBgn0027498.
DR   EnsemblMetazoa; FBtr0332383; FBpp0304657; FBgn0027498.
DR   GeneID; 32042; -.
DR   KEGG; dme:Dmel_CG2061; -.
DR   UCSC; CG2061-RA; d. melanogaster.
DR   FlyBase; FBgn0027498; CG2061.
DR   VEuPathDB; VectorBase:FBgn0027498; -.
DR   eggNOG; KOG2787; Eukaryota.
DR   GeneTree; ENSGT00530000063186; -.
DR   HOGENOM; CLU_036244_0_1_1; -.
DR   InParanoid; Q9Y0Y7; -.
DR   OMA; CTRAEEW; -.
DR   OrthoDB; 681208at2759; -.
DR   PhylomeDB; Q9Y0Y7; -.
DR   BioGRID-ORCS; 32042; 0 hits in 3 CRISPR screens.
DR   GenomeRNAi; 32042; -.
DR   PRO; PR:Q9Y0Y7; -.
DR   Proteomes; UP000000803; Chromosome X.
DR   Bgee; FBgn0027498; Expressed in testis and 21 other tissues.
DR   ExpressionAtlas; Q9Y0Y7; differential.
DR   Genevisible; Q9Y0Y7; DM.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 1.50.10.10; -; 1.
DR   InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR   InterPro; IPR007822; LANC-like.
DR   InterPro; IPR020464; LanC-like_prot_euk.
DR   Pfam; PF05147; LANC_like; 1.
DR   PRINTS; PR01951; LANCEUKARYTE.
DR   PRINTS; PR01950; LANCSUPER.
DR   SMART; SM01260; LANC_like; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..419
FT                   /note="LanC-like protein 3 homolog"
FT                   /id="PRO_0000285253"
SQ   SEQUENCE   419 AA;  47610 MW;  8341FC58698FCC93 CRC64;
     MERRYLKNPF PDFAGGENTP FASDEEHIKN LICTYVDAIL EHCHPNSDDE DNRGDLYVGN
     AGIAFMFWKL NSCEQTRDLY PALDHAASFI RNAKVNANRY KKRSAERYSF LCGNAGIYAV
     SAAISQALKE TEELSDDLAN FKSGIPCSKE FMHTKYGCDE VLVGRAGYLS GCYWLNDVLP
     EKKITDDDLV SICQLIVTSG REYSKQNNSP CPLMYQYHGT EYLGAAHGLC AILHMLLDSP
     WFRTLPISAP AAELRDIKRS IDFFLELQDS DGNFPVALED LRSGRDKRLV HWCHGAPGAV
     YVLAKAYLIF KEEKYLASLR RCADMVWKKG FLRKGPGICH GVAGNGYVFL LLFRLTNEMR
     YLYRAHKFME LLTNAEFKLR ARTPDRPHSL YEGVAGTVCY LVDLLEPEQA YFPFMDVFH