ID   LAPA_HAEIN              Reviewed;          97 AA.
AC   P44129;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Probable lipopolysaccharide assembly protein A {ECO:0000255|HAMAP-Rule:MF_01948};
GN   Name=lapA {ECO:0000255|HAMAP-Rule:MF_01948}; OrderedLocusNames=HI_1222;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Involved in the assembly of lipopolysaccharide (LPS).
CC       {ECO:0000255|HAMAP-Rule:MF_01948}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01948}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01948}.
CC   -!- SIMILARITY: Belongs to the LapA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01948}.
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DR   EMBL; L42023; AAC22875.1; -; Genomic_DNA.
DR   PIR; C64022; C64022.
DR   RefSeq; NP_439378.1; NC_000907.1.
DR   RefSeq; WP_005650128.1; NC_000907.1.
DR   AlphaFoldDB; P44129; -.
DR   SMR; P44129; -.
DR   STRING; 71421.HI_1222; -.
DR   EnsemblBacteria; AAC22875; AAC22875; HI_1222.
DR   KEGG; hin:HI_1222; -.
DR   PATRIC; fig|71421.8.peg.1274; -.
DR   eggNOG; COG3771; Bacteria.
DR   HOGENOM; CLU_160072_0_0_6; -.
DR   OMA; QGDYRIS; -.
DR   BioCyc; HINF71421:G1GJ1-1253-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0008653; P:lipopolysaccharide metabolic process; IEA:InterPro.
DR   HAMAP; MF_01948; LPS_assembly_LapA; 1.
DR   InterPro; IPR032906; LapA.
DR   InterPro; IPR010445; LapA_dom.
DR   Pfam; PF06305; LapA_dom; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Coiled coil; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..97
FT                   /note="Probable lipopolysaccharide assembly protein A"
FT                   /id="PRO_0000168888"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01948"
FT   TRANSMEM        46..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01948"
FT   COILED          67..95
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01948"
SQ   SEQUENCE   97 AA;  10915 MW;  506D6A897A597872 CRC64;
     MIKYILGIVI FIAIVLVAIT IGANNDQIIT FNYIVAESQF QLSSLVAILF GLGLILGWLI
     TAFFYIKLKL KNMALARQVK RQTLQINELT TTRDKVV