ID   LAPT_MANHA              Reviewed;         237 AA.
AC   P49618;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Arginine-binding periplasmic protein;
DE   Flags: Precursor;
GN   Name=lapT;
OS   Mannheimia haemolytica (Pasteurella haemolytica).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Mannheimia.
OX   NCBI_TaxID=75985;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Serotype A1 / PH101;
RX   PubMed=8359916; DOI=10.1128/iai.61.9.3942-3951.1993;
RA   Highlander S.K., Wickersham E.A., Garza O., Weinstock G.M.;
RT   "Expression of the Pasteurella haemolytica leukotoxin is inhibited by a
RT   locus that encodes an ATP-binding cassette homolog.";
RL   Infect. Immun. 61:3942-3951(1993).
RN   [2]
RP   ERRATUM OF PUBMED:8359916.
RA   Highlander S.K., Wickersham E.A., Garza O., Weinstock G.M.;
RL   Infect. Immun. 61:5431-5431(1993).
CC   -!- FUNCTION: Binds arginine; part of the arginine periplasmic transport
CC       system.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein 3 family.
CC       {ECO:0000305}.
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DR   EMBL; M59210; AAA25536.1; -; Genomic_DNA.
DR   AlphaFoldDB; P49618; -.
DR   SMR; P49618; -.
DR   STRING; 75985.WC39_13360; -.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0015276; F:ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   InterPro; IPR001320; Iontro_rcpt.
DR   InterPro; IPR018313; SBP_3_CS.
DR   InterPro; IPR001638; Solute-binding_3/MltF_N.
DR   Pfam; PF00497; SBP_bac_3; 1.
DR   SMART; SM00062; PBPb; 1.
DR   SMART; SM00079; PBPe; 1.
DR   PROSITE; PS01039; SBP_BACTERIAL_3; 1.
PE   3: Inferred from homology;
KW   Amino-acid transport; Periplasm; Signal; Transport.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..237
FT                   /note="Arginine-binding periplasmic protein"
FT                   /id="PRO_0000031766"
SQ   SEQUENCE   237 AA;  26514 MW;  298BF085CC5A0293 CRC64;
     MKKTLLTLLF GCVVTAQAQD IIVMEPSYPP FEMTEEKGEI IGFDVDIANA ICKEMNANCT
     FHSQPFDSLI QSLKQKQFDA AISGMGITEP RKKQVLFSEP YFPSSAAFIA KKDTDFAKVK
     TIGVQNGTTY QHYLAKEKKE YNVKSYASYQ NAILDVQNGR IDAIFGDVPV LAEMARKHEG
     LDFVGEKINN PNYFGDGLGI ATHLKNQVLV DQFNAALKTI KENGEYQKIY DKWMGGK